Monitoring kinetics reveals critical parameters of IgA-dependent granulocyte-mediated anti-tumor cell cytotoxicity.

Antibody-Dependent Cell Cytotoxicity CD47 Antigen / analysis Cytotoxicity, Immunologic ErbB Receptors / analysis Granulocytes / immunology Humans Immunoglobulin A / immunology Intercellular Adhesion Molecule-1 / analysis Kinetics Neutrophils / immunology
EGFR Granulocyte cytotoxicity assay HNSCC IgA Immunotherapy Impedance

Journal

Journal of immunological methods
ISSN: 1872-7905
Titre abrégé: J Immunol Methods
Pays: Netherlands
ID NLM: 1305440

Informations de publication

Date de publication:
10 2019
Historique:
received: 17 01 2019
revised: 26 06 2019
accepted: 08 08 2019
pubmed: 14 8 2019
medline: 7 5 2020
entrez: 13 8 2019
Statut: ppublish

Résumé

Human IgA antibodies effectively engage myeloid cells for the FcαRI-dependent antibody-dependent cell-mediated cytotoxicity (ADCC) of tumor cells. Established methods to investigate ADCC are the

Identifiants

DOI: 10.1016/j.jim.2019.112644 PMID: 31404549
pubmed: 31404549
pii: S0022-1759(19)30021-3
doi: 10.1016/j.jim.2019.112644
pii:
doi:

Substances chimiques

CD47 Antigen 0
ICAM1 protein, human 0
Immunoglobulin A 0
Intercellular Adhesion Molecule-1 126547-89-5
EGFR protein, human EC 2.7.10.1
ErbB Receptors EC 2.7.10.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

112644

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Anabel Zwick (A)

Institute of Virology, Saarland University Medical Center, 66421 Homburg, Germany.

Muriel Bernhard (M)

Institute of Virology, Saarland University Medical Center, 66421 Homburg, Germany.

Arne Knoerck (A)

Department of Biophysics, Center of Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, 66421 Homburg, Germany.

Maximilian Linxweiler (M)

Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Saar, Germany.

Bernhard Schick (B)

Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, 66421 Homburg, Saar, Germany.

Joana Heinzelmann (J)

Department of Urology, Saarland University Medical Center, 66421 Homburg, Saar, Germany.

Sigrun Smola (S)

Institute of Virology, Saarland University Medical Center, 66421 Homburg, Germany.

Stefan Lohse (S)

Institute of Virology, Saarland University Medical Center, 66421 Homburg, Germany. Electronic address: stefan.lohse@uni-saarland.de.

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Classifications MeSH

questionsmedicales.fr › Phénomènes du système immunitaire › Cytotoxicité immunologique › Cytotoxicité à médiation cellulaire dépendante des anticorps › Monitoring kinetics reveals critical...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Antigènes CD47 › Monitoring kinetics reveals critical...
questionsmedicales.fr › Phénomènes du système immunitaire › Cytotoxicité immunologique › Monitoring kinetics reveals critical...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur facteur croissance › Récepteurs ErbB › Monitoring kinetics reveals critical...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Granulocytes › Monitoring kinetics reveals critical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Monitoring kinetics reveals critical...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline A › Monitoring kinetics reveals critical...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Molécule-1 d'adhérence intercellulaire › Monitoring kinetics reveals critical...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Monitoring kinetics reveals critical...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Granulocytes neutrophiles › Monitoring kinetics reveals critical...