Current status of use of big data and artificial intelligence in RMDs: a systematic literature review informing EULAR recommendations.


Journal

RMD open
ISSN: 2056-5933
Titre abrégé: RMD Open
Pays: England
ID NLM: 101662038

Informations de publication

Date de publication:
2019
Historique:
received: 09 05 2019
revised: 26 06 2019
accepted: 29 06 2019
entrez: 16 8 2019
pubmed: 16 8 2019
medline: 16 8 2019
Statut: epublish

Résumé

To assess the current use of big data and artificial intelligence (AI) in the field of rheumatic and musculoskeletal diseases (RMDs). A systematic literature review was performed in PubMed MEDLINE in November 2018, with key words referring to big data, AI and RMDs. All original reports published in English were analysed. A mirror literature review was also performed outside of RMDs on the same number of articles. The number of data analysed, data sources and statistical methods used (traditional statistics, AI or both) were collected. The analysis compared findings within and beyond the field of RMDs. Of 567 articles relating to RMDs, 55 met the inclusion criteria and were analysed, as well as 55 articles in other medical fields. The mean number of data points was 746 million (range 2000-5 billion) in RMDs, and 9.1 billion (range 100 000-200 billion) outside of RMDs. Data sources were varied: in RMDs, 26 (47%) were clinical, 8 (15%) biological and 16 (29%) radiological. Both traditional and AI methods were used to analyse big data (respectively, 10 (18%) and 45 (82%) in RMDs and 8 (15%) and 47 (85%) out of RMDs). Machine learning represented 97% of AI methods in RMDs and among these methods, the most represented was artificial neural network (20/44 articles in RMDs). Big data sources and types are varied within the field of RMDs, and methods used to analyse big data were heterogeneous. These findings will inform a European League Against Rheumatism taskforce on big data in RMDs.

Identifiants

pubmed: 31413871
doi: 10.1136/rmdopen-2019-001004
pii: rmdopen-2019-001004
pmc: PMC6668041
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't Systematic Review

Langues

eng

Pagination

e001004

Déclaration de conflit d'intérêts

Competing interests: RC is an employee of Orange Healthcare, and HS is an employee of Sanoïa, a Digital CRO providing clinical research services including data science. There are no competing interests for the other authors.

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Auteurs

Joanna Kedra (J)

Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.
Rheumatology Department, Hôpital Universitaire Pitié Salpêtrière, APHP, Paris, France.

Timothy Radstake (T)

Department of Rheumatology, Clinical Immunology and Laboratory for Translational Immunology, University of Utrecht Faculty of Medicine, Utrecht, The Netherlands.

Aridaman Pandit (A)

Department of Rheumatology, Clinical Immunology and Laboratory for Translational Immunology, University of Utrecht Faculty of Medicine, Utrecht, The Netherlands.

Xenofon Baraliakos (X)

Herne, Ruhr-University, Rheumazentrum Ruhrgebiet, Bochum, Germany.

Francis Berenbaum (F)

Rheumatology Department, Hospital Saint-Antoine, APHP, Paris, Île-de-France, France.

Axel Finckh (A)

Division of Rheumatology, University Hospital of Geneva, Geneva, Switzerland.

Bruno Fautrel (B)

Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.
Rheumatology Department, Hôpital Universitaire Pitié Salpêtrière, APHP, Paris, France.

Tanja A Stamm (TA)

Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

David Gomez-Cabrero (D)

Departamento de Salud-Universidad Pública de Navarra, Translational Bioinformatics Unit, Navarra Biomed, Pamplona, Spain.

Christian Pristipino (C)

Interventional Cardiology Department, Ospedale San Filippo Neri, Rome, Italy.

Remy Choquet (R)

Orange e-Health, INSERM U1142, Paris, France.

Hervé Servy (H)

e-Health Services, Sanoïa, Gardanne, France.

Simon Stones (S)

School of Healthcare, University of Leeds, Leeds, West Yorkshire, UK.

Gerd Burmester (G)

Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany.

Laure Gossec (L)

Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S 1136, Sorbonne Universite, Paris, France.
Rheumatology Department, Hôpital Universitaire Pitié Salpêtrière, APHP, Paris, France.

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