A Patient with Type 3 Autoimmune Polyglandular Syndrome who Developed Systemic Lupus Erythematosus 8 years after the Diagnosis of Autoimmune Hepatitis.
Anti-Inflammatory Agents
/ administration & dosage
Cyclophosphamide
/ administration & dosage
Female
Hepatitis, Autoimmune
/ complications
Humans
Immunosuppressive Agents
/ administration & dosage
Lupus Erythematosus, Systemic
/ complications
Middle Aged
Polyendocrinopathies, Autoimmune
/ complications
Prednisolone
/ administration & dosage
autoimmune hepatitis
autoimmune polyglandular syndrome type 3
chronic thyroiditis
slowly progressive insulin-dependent diabetes mellitus
systemic lupus erythematosus
Journal
Acta medica Okayama
ISSN: 0386-300X
Titre abrégé: Acta Med Okayama
Pays: Japan
ID NLM: 0417611
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
entrez:
24
8
2019
pubmed:
24
8
2019
medline:
7
2
2020
Statut:
ppublish
Résumé
Eight years prior to her present admission, a 61-year-old Japanese woman was diagnosed with autoimmune hepatitis, slowly progressive insulin-dependent diabetes mellitus, and chronic thyroiditis; she had been treated with oral prednisolone (PSL). After she suddenly discontinued PSL, she newly developed systemic lupus erythematosus. A combination therapy of oral PSL and intravenous cyclophosphamide resulted in remission. She was finally diagnosed with autoimmune polyglandular syndrome (APS) type 3 (3A ,3B, 3D), complicated with four different autoimmune diseases. Since patients with type 3 APS may present many manifestations over a long period of time, they should be carefully monitored.
Substances chimiques
Anti-Inflammatory Agents
0
Immunosuppressive Agents
0
Cyclophosphamide
8N3DW7272P
Prednisolone
9PHQ9Y1OLM
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
367-372Déclaration de conflit d'intérêts
No potential conflict of interest relevant to this article was reported.
Références
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