Post-column reaction with a 3D-printed two-stage microreactor and flame ionization detection for carbon compound independent response in fast gas chromatography.

3D-printed microreactor Fast gas chromatography Pneumatic switching device Post-column gas chromatography

Journal

Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488

Informations de publication

Date de publication:
04 Jan 2020
Historique:
received: 15 04 2019
revised: 08 08 2019
accepted: 13 08 2019
pubmed: 26 8 2019
medline: 3 3 2020
entrez: 26 8 2019
Statut: ppublish

Résumé

Fast gas chromatography that leverages the high chromatographic efficiency of narrow bore capillary column technology and temperature programming was successfully integrated with a third-generation low void-volume, 3D-printed two-stage microreactor. Effective management of extra-column effect and the capability to perform post-column backflushing were achieved with the incorporation of a recently commercialized, electronically controlled pneumatic switching device and a deactivated metal three-way microdevice. With this configuration, narrow bore capillary columns having internal diameters between 0.10 and 0.15 mm can be employed to produce chromatographic peaks in the domain of fast gas chromatography, with peak widths at half-height ranging from 0.42 s to 0.92 s for probe compounds having k over a range from 1.7 for toluene to 60 with the last analyte (nC

Identifiants

pubmed: 31445802
pii: S0021-9673(19)30847-7
doi: 10.1016/j.chroma.2019.460460
pii:
doi:

Substances chimiques

Carbon 7440-44-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

460460

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Jim Luong (J)

Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta T8L 2P4, Canada; Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75 Hobart 7001 Australia. Electronic address: luong@dow.com.

Yujuan Hua (Y)

Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta T8L 2P4, Canada.

Ronda Gras (R)

Dow Chemical Canada ULC, Highway 15, Fort Saskatchewan, Alberta T8L 2P4, Canada; Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Private Bag 75 Hobart 7001 Australia.

Xiuhan Yang (X)

Dow Chemical China Investment Co., Ltd., No. 936 Zhangheng Road, Shanghai 201203, China.

Peilin Yang (P)

Dow Chemical USA, Analytical Science, Collegeville, PA 19426, USA.

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Classifications MeSH