Placental mesenchymal dysplasia with a good outcome: A case report.
etiology
hydatidiform mole
placental mesenchymal dysplasia
prognosis
ultrasonography
Journal
The journal of obstetrics and gynaecology research
ISSN: 1447-0756
Titre abrégé: J Obstet Gynaecol Res
Pays: Australia
ID NLM: 9612761
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
14
02
2019
accepted:
28
07
2019
pubmed:
27
8
2019
medline:
1
4
2020
entrez:
27
8
2019
Statut:
ppublish
Résumé
Placental mesenchymal dysplasia (PMD), characterized by an enlarged and thickened placenta with multiple hypoechoic cystic spaces, frequently leads to a poor infantile/fetal outcome. Here, we describe a case of PMD involving an infant delivered at term with a good outcome. The fetus was male, and the proportion of the PMD lesion to the entire placenta remained constant: the PMD lesion did not enlarge. Given what is known about the pathogenesis of PMD with its association with vascular endothelial growth factor-D (VEGF-D) encoded by an X-linked gene and androgenetic/biparental mosaicism, which is consistent with female dominancy and a poor outcome, we suggest that a male sex of the fetus and non-progressing PMD may have been associated with this good outcome.
Substances chimiques
VEGFD protein, human
0
Vascular Endothelial Growth Factor D
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
2284-2288Informations de copyright
© 2019 Japan Society of Obstetrics and Gynecology.
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