Use of labor induction with dinoprostone vaginal suppositories in pregnant women with gestational hypertension.
Administration, Intravaginal
Adult
Delivery, Obstetric
/ statistics & numerical data
Dinoprostone
/ administration & dosage
Female
Humans
Hypertension, Pregnancy-Induced
/ therapy
Labor, Induced
/ methods
Labor, Obstetric
/ drug effects
Oxytocics
/ administration & dosage
Pregnancy
Pregnancy Outcome
Retrospective Studies
Suppositories
dinoprostone suppository
gestational hypertension
labor induction
pregnancy
prostaglandin E2
Journal
The journal of obstetrics and gynaecology research
ISSN: 1447-0756
Titre abrégé: J Obstet Gynaecol Res
Pays: Australia
ID NLM: 9612761
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
24
04
2019
accepted:
28
07
2019
pubmed:
29
8
2019
medline:
1
4
2020
entrez:
29
8
2019
Statut:
ppublish
Résumé
Gestational hypertension is a common disorder of pregnancy. This study aims to evaluate the effect of labor induction with dinoprostone vaginal suppositories (Propess) on pregnancy outcomes in pregnant women with gestational hypertension. The retrospective study included 375 patients with gestational hypertension. All patients were included into three groups according to the characteristics at admission. Women who had initiated labor spontaneously at admission were enrolled in Spontaneous labor group. According to Bishop score, other patients underwent labor induction with Propess or oxytocin were enrolled in Propess group or Oxytocin group. Demographic information and perinatal outcome data were collected. The vaginal delivery rate of the women with gestational hypertension was respectively 93.5% (Spontaneous labor group), 77.0% (Propess group), and 52.5% (Oxytocin group) in three groups with significant difference (P < 0.001). The duration of labor was 8.29 ± 3.70 h (Spontaneous labor group), 8.45 ± 5.21 h (Propess group) and 12.37 ± 11.47 h (Oxytocin group) in three groups, respectively. No differences were found in the intrapartum fever (P = 0.588), intrapartum hemorrhage (P = 0.953), intrapartum maximum blood pressure (P = 0.301 and P = 0.535) and post-partum hemorrhage (P = 0.075) among three groups. Neonatal outcomes were similar among three groups (Neonatal hospitalization rate, P = 0.437; 1-min Apgar score, P = 0.304; 5-min Apgar score, P = 0.340; Birth weight, P = 0.089). No poor maternal and neonatal outcomes occurred. Pregnant women with gestational hypertension could have favorable pregnancy outcomes. Using Propess as a mode of labor induction in gestational hypertension is safe and effective, without increasing intrapartum blood pressure and inducing poor pregnancy outcomes.
Substances chimiques
Oxytocics
0
Suppositories
0
Dinoprostone
K7Q1JQR04M
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2185-2192Informations de copyright
© 2019 Japan Society of Obstetrics and Gynecology.
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