Streamlined

Bacterial Proteins / genetics Biomass Genome, Bacterial Glycerol / metabolism Metabolic Engineering Mutagenesis Phenol / chemistry Plasmids / genetics Pseudomonas / genetics Solvents / chemistry
Pseudomonas genome reduction metabolic engineering phenol solvent tolerance streamlined chassis

Journal

ACS synthetic biology
ISSN: 2161-5063
Titre abrégé: ACS Synth Biol
Pays: United States
ID NLM: 101575075

Informations de publication

Date de publication:
20 09 2019
Historique:
pubmed: 30 8 2019
medline: 3 7 2020
entrez: 30 8 2019
Statut: ppublish

Résumé

Microbes harbor many traits that are dispensable or even unfavorable under industrial and laboratory settings. The elimination of such traits could improve the host's efficiency, genetic stability, and robustness, thereby increasing the predictability and boosting its performance as a microbial cell factory. We engineered solvent-tolerant

Identifiants

DOI: 10.1021/acssynbio.9b00108 PMID: 31465206
pubmed: 31465206
doi: 10.1021/acssynbio.9b00108
doi:

Substances chimiques

Bacterial Proteins 0
Solvents 0
Phenol 339NCG44TV
Glycerol PDC6A3C0OX

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

2036-2050

Auteurs

Benedikt Wynands (B)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.
Institute of Bio- and Geosciences, IBG-1: Biotechnology , Forschungszentrum Jülich GmbH , 52425 Jülich , Germany.
ORCID: 0000-0001-8599-3205

Maike Otto (M)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.
Institute of Bio- and Geosciences, IBG-1: Biotechnology , Forschungszentrum Jülich GmbH , 52425 Jülich , Germany.
ORCID: 0000-0001-6858-029X

Nadine Runge (N)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.

Sarah Preckel (S)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.

Tino Polen (T)

Institute of Bio- and Geosciences, IBG-1: Biotechnology , Forschungszentrum Jülich GmbH , 52425 Jülich , Germany.

Lars M Blank (LM)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.

Nick Wierckx (N)

Institute of Applied Microbiology , RWTH Aachen University , Worringerweg 1 , 52074 Aachen , Germany.
Institute of Bio- and Geosciences, IBG-1: Biotechnology , Forschungszentrum Jülich GmbH , 52425 Jülich , Germany.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Streamlined
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biomasse › Streamlined
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome bactérien › Streamlined
questionsmedicales.fr › Glucides › Polyols › Dérivés du glycérol › Glycérol › Streamlined
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Génie métabolique › Streamlined
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Streamlined
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Phénol › Streamlined
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Plasmides › Streamlined
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Pseudomonadaceae › Pseudomonas › Streamlined
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Solvants › Streamlined