Choroidal juxtapapillary neovascularization regression in multiple evanescent white dot syndrome by optical coherence tomography angiography: a case report.


Journal

Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382

Informations de publication

Date de publication:
31 Aug 2019
Historique:
received: 29 01 2019
accepted: 30 07 2019
entrez: 1 9 2019
pubmed: 1 9 2019
medline: 6 2 2020
Statut: epublish

Résumé

Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur. Here, we describe a case of a 22-year-old white Caucasian man with blurred vision in his left eye who exhibited juxtapapillary choroidal neovascularization on optical coherence tomography angiography. Although multiple evanescent white dot syndrome is often self-limiting, to reduce the possibility of an inflammatory reaction, we preferred to administer prednisolone orally. After 3 months, significant regression of juxtapapillary neovascularization was observed by B-scan and optical coherence tomography angiography. Symptoms resolved in 3 months. A steady situation was observed at 4 years of follow-up. This case report highlights the helpful use of optical coherence tomography angiography in daily clinical practice, even in inflammatory diseases, such as atypical juxtapapillary neovascularization in multiple evanescent white dot syndrome. Choroidal neovascularization associated with multiple evanescent white dot syndrome by means of optical coherence tomography angiography showed neovascular activity regression, thus avoiding invasive therapy.

Sections du résumé

BACKGROUND BACKGROUND
Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.
CASE PRESENTATION METHODS
Here, we describe a case of a 22-year-old white Caucasian man with blurred vision in his left eye who exhibited juxtapapillary choroidal neovascularization on optical coherence tomography angiography. Although multiple evanescent white dot syndrome is often self-limiting, to reduce the possibility of an inflammatory reaction, we preferred to administer prednisolone orally. After 3 months, significant regression of juxtapapillary neovascularization was observed by B-scan and optical coherence tomography angiography. Symptoms resolved in 3 months. A steady situation was observed at 4 years of follow-up.
CONCLUSION CONCLUSIONS
This case report highlights the helpful use of optical coherence tomography angiography in daily clinical practice, even in inflammatory diseases, such as atypical juxtapapillary neovascularization in multiple evanescent white dot syndrome. Choroidal neovascularization associated with multiple evanescent white dot syndrome by means of optical coherence tomography angiography showed neovascular activity regression, thus avoiding invasive therapy.

Identifiants

pubmed: 31470898
doi: 10.1186/s13256-019-2211-8
pii: 10.1186/s13256-019-2211-8
pmc: PMC6717392
doi:

Substances chimiques

Glucocorticoids 0
Prednisolone 9PHQ9Y1OLM

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

274

Références

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pubmed: 20718788
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pubmed: 22418228
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pubmed: 24136134
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pubmed: 27327289
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Auteurs

Maria Cristina Savastano (MC)

Centro Italiano Macula, Via Angelo Brofferio, 7, 00196, Rome, Italy. mariacristina.savastano@gmail.com.

Marco Rispoli (M)

Centro Italiano Macula, Via Angelo Brofferio, 7, 00196, Rome, Italy.

Bruno Lumbroso (B)

Centro Italiano Macula, Via Angelo Brofferio, 7, 00196, Rome, Italy.

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Classifications MeSH