Endocrine Outcomes After Pituitary Surgery.

Humans Hypothalamo-Hypophyseal System / physiopathology Pituitary Diseases / physiopathology Pituitary Neoplasms / physiopathology Pituitary-Adrenal System / physiopathology Postoperative Complications Treatment Outcome
Adrenal insufficiency Growth hormone Hypogonadism Pituitary surgery Prolactin

Journal

Neurosurgery clinics of North America
ISSN: 1558-1349
Titre abrégé: Neurosurg Clin N Am
Pays: United States
ID NLM: 9008004

Informations de publication

Date de publication:
Oct 2019
Historique:
entrez: 1 9 2019
pubmed: 1 9 2019
medline: 23 2 2020
Statut: ppublish

Résumé

Although removal of pituitary tumors yields excellent surgical outcomes, perturbations in the hypothalamic-pituitary axis are not uncommon. Careful assessment of postoperative hormone status with supplementation or further medical therapy is critical to successful outcomes. Although many centers routinely use perioperative steroids, they can be associated with worse outcomes in the absence of intact preoperative adrenal function or damage to the pituitary gland or stalk during surgery. Postoperative assessment of prolactin, cortisol, and growth hormone can be prognostic of surgical cure. Hormonal axes should be reevaluated routinely several weeks after surgery, because longitudinal monitoring is important for surgical and medical outcomes.

Identifiants

DOI: 10.1016/j.nec.2019.05.009 PMID: 31471056
pubmed: 31471056
pii: S1042-3680(19)30045-2
doi: 10.1016/j.nec.2019.05.009
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

491-498

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Anshu Buttan (A)

Department of Medicine, Division of Endocrinology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Becker B-131, Los Angeles, CA 90048, USA.

Adam N Mamelak (AN)

Department of Neurosurgery, Cedars-Sinai Medical Center, 127 S San Vicente Boulevard, A6600, Los Angeles, CA 90048, USA. Electronic address: Adam.Mamelak@cshs.org.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › Système nerveux › Système neuroendocrinien › Axe hypothalamohypophysaire › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Tumeurs de l'hypophyse › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › Système endocrine › Glandes endocrines › Axe hypophyso-surrénalien › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Complications postopératoires › Endocrine Outcomes After Pituitary Surgery.
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Endocrine Outcomes After Pituitary Surgery.