Sensory dysregulation in tic disorders is associated with executive dysfunction and comorbidities.
Adolescent
Case-Control Studies
Child
Child, Preschool
Comorbidity
Cross-Sectional Studies
Developmental Disabilities
/ complications
Executive Function
Female
Humans
Male
Mental Disorders
/ complications
Prevalence
Psychiatric Status Rating Scales
Quality of Life
Sensation Disorders
/ complications
Surveys and Questionnaires
Tic Disorders
/ complications
child
executive dysfunction
neurodevelopmental disorders
sensory dysregulation
tic disorders
Journal
Movement disorders : official journal of the Movement Disorder Society
ISSN: 1531-8257
Titre abrégé: Mov Disord
Pays: United States
ID NLM: 8610688
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
18
04
2019
revised:
04
07
2019
accepted:
19
07
2019
pubmed:
11
9
2019
medline:
23
6
2020
entrez:
11
9
2019
Statut:
ppublish
Résumé
Tics are conceptualized as a sensorimotor phenomenon with a premonitory urge typically described by patients. As observed in other neurodevelopmental disorders, we have observed sensory dysregulation symptoms, such as tactile hypersensitivity to clothing, in children with tic disorders; however, formal clinical research in this area is limited. To define the presence of sensory dysregulation symptoms in tic disorders, and their clinical associations. Prevalence of sensory dysregulation in 102 children with tic disorders was compared to 61 age- and sex-matched healthy controls. Sensory dysregulation, executive function, and quality of life data were obtained through the Short Sensory Profile-2, Sensory Profile-2, Sensory Processing Measure, Behaviour Rating Inventory of Executive Function-2, and Strength and Difficulties Questionnaire and Pediatric Quality of Life Inventory. Tics were assessed with the Yale Global Tic Severity Scale. Children with tics, in the presence of comorbidity, had elevated sensory dysregulation compared to healthy controls (P < 0.001). There was a positive correlation between sensory dysregulation and global executive difficulties in children with tics and comorbidity (n = 87; rho = 0.716; P < 0.001) and a negative correlation of sensory dysregulation with quality of life (n = 87; rho = -0.595; P < 0.001). In children with tics, there was an association between sensory dysregulation and number of comorbidities (P < 0.001). In the presence of comorbidity, children with tic disorders have broad sensory dysregulation symptoms beyond the premonitory urge. There was a statistically significant association between sensory dysregulation and executive function difficulties and the presence of neurodevelopmental and psychiatric comorbidity. Sensory dysregulation can be considered neurodevelopmental symptoms, providing insight into the neurobiology of tics and opportunities for therapeutic intervention. © 2019 International Parkinson and Movement Disorder Society.
Sections du résumé
BACKGROUND
Tics are conceptualized as a sensorimotor phenomenon with a premonitory urge typically described by patients. As observed in other neurodevelopmental disorders, we have observed sensory dysregulation symptoms, such as tactile hypersensitivity to clothing, in children with tic disorders; however, formal clinical research in this area is limited.
OBJECTIVE
To define the presence of sensory dysregulation symptoms in tic disorders, and their clinical associations.
METHODS
Prevalence of sensory dysregulation in 102 children with tic disorders was compared to 61 age- and sex-matched healthy controls. Sensory dysregulation, executive function, and quality of life data were obtained through the Short Sensory Profile-2, Sensory Profile-2, Sensory Processing Measure, Behaviour Rating Inventory of Executive Function-2, and Strength and Difficulties Questionnaire and Pediatric Quality of Life Inventory. Tics were assessed with the Yale Global Tic Severity Scale.
RESULTS
Children with tics, in the presence of comorbidity, had elevated sensory dysregulation compared to healthy controls (P < 0.001). There was a positive correlation between sensory dysregulation and global executive difficulties in children with tics and comorbidity (n = 87; rho = 0.716; P < 0.001) and a negative correlation of sensory dysregulation with quality of life (n = 87; rho = -0.595; P < 0.001). In children with tics, there was an association between sensory dysregulation and number of comorbidities (P < 0.001).
CONCLUSION
In the presence of comorbidity, children with tic disorders have broad sensory dysregulation symptoms beyond the premonitory urge. There was a statistically significant association between sensory dysregulation and executive function difficulties and the presence of neurodevelopmental and psychiatric comorbidity. Sensory dysregulation can be considered neurodevelopmental symptoms, providing insight into the neurobiology of tics and opportunities for therapeutic intervention. © 2019 International Parkinson and Movement Disorder Society.
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1901-1909Informations de copyright
© 2019 International Parkinson and Movement Disorder Society.
Références
Leckman JF, Bloch MH, Sukhodolsky DG, Scahill L, King RA. Phenomenology of tics and sensory urges: the self under siege. In: Tourette Syndrome. Oxford, UK: Oxford University Press; 2013:3-25.
O'Hare D, Helmes E, Eapen V, Grove R, McBain K, Reece J. The impact of tic severity, comorbidity and peer attachment on quality of life outcomes and functioning in Tourette's syndrome: parental perspectives. Child Psychiatry Hum Dev 2016;47:563-573.
Reese HE, Scahill L, Peterson AL, et al. The premonitory urge to tic: measurement, characteristics, and correlates in older adolescents and adults. Behav Ther. 2014;45:177-186.
Cavanna AE, Black KJ, Hallett M, Voon V. Neurobiology of the premonitory urge in Tourette's syndrome: pathophysiology and treatment implications. J Neuropsychiatry Clin Neurosci 2017;29:95-104.
Cohen SC, Leckman JF, Bloch MH. Clinical assessment of Tourette syndrome and tic disorders. Neurosci Biobehav Rev 2013;37:997-1007.
Jewers R, Staley D, Shady G. Sensory processing differences in children diagnosed with Tourette's disorder. Occup Ther Ment Health 2013;29:385-394.
Weisman H, Parush S, Apter A, Fennig S, Benaroya-Milshtein N, Steinberg T. A study of sensory dysregulation in children with tic disorders. J Neural Transm (Vienna) 2018;125:1077-1085.
Belluscio BA, Jin L, Watters V, Lee TH, Hallett M. Sensory sensitivity to external stimuli in Tourette syndrome patients. Mov Disord 2011;26:2538-2543.
Cox JH, Seri S, Cavanna AE. Sensory aspects of Tourette syndrome. Neurosci Biobehav Rev 2018;88:170-176.
Houghton DC, Capriotti MR, Conelea CA, Woods DW. Sensory phenomena in Tourette syndrome: their role in symptom formation and treatment. Curr Dev Disord Rep 2014;1:245-251.
Lane SJ, Miller LJ, Hanft BE. Toward a consensus in terminology in sensory integration theory and practice: part 2: sensory integration patterns of function and dysfunction. Sens Integration Special Interest Section Q 2000;23:1-4.
Koomar J, Bundy A. The art and science of creating direct intervention from theory. In: Sensory Integration: Theory and Practice. Philadelphia, PA: F.A. Davis; 1991:251-317.
Orth M, Munchau A. Transcranial magnetic stimulation studies of sensorimotor networks in Tourette syndrome. Behav Neurol. 2013;27:57-64.
Tomchek SD, Dunn W. Sensory processing in children with and without autism: a comparative study using the short sensory profile. Am J Occup Ther 2007;61:190-200.
Bijlenga D, Tjon-Ka-Jie JYM, Schuijers F, Kooij JJS. Atypical sensory profiles as core features of adult ADHD, irrespective of autistic symptoms. Eur Psychiatry 2017;43:51-57.
Gouze KR, Hopkins J, LeBailly SA, Lavigne JV. Re-examining the epidemiology of sensory regulation dysfunction and comorbid psychopathology. J Abnorm Child Psychol 2009;37:1077-1087.
Chien CW, Rodger S, Copley J, Branjerdporn G, Taggart C. Sensory processing and its relationship with children's daily life participation. Phys Occup Ther Pediatr 2016;36:73-87.
Parham LD, Mailloux, Z. Sensory integration. In: Case-Smith J, ed. Occupational Therapy for Children. St Louis, Mo: Mosby/Elsevier: 2001:329-381.
Castellanos FX, Fine EJ, Kaysen D, Marsh WL, Rapoport JL, Hallett M. Sensorimotor gating in boys with Tourette's syndrome and ADHD: preliminary results. Biol Psychiatry 1996;39:33-41.
Biermann-Ruben K, Miller A, Franzkowiak S, et al. Increased sensory feedback in Tourette syndrome. Neuroimage 2012;63:119-125.
Thomalla G, Jonas M, Baumer T, et al. Costs of control: decreased motor cortex engagement during a Go/NoGo task in Tourette's syndrome. Brain 2014;137:122-136.
Liu Y, Miao W, Wang J, et al. Structural abnormalities in early Tourette syndrome children: a combined voxel-based morphometry and tract-based spatial statistics study. PLoS One 2013;8:e76105.
da Silva Prado H, do Rosario MC, Lee J, Hounie AG, Shavitt RG, Miguel EC. Sensory phenomena in obsessive-compulsive disorder and tic disorders: a review of the literature. CNS Spectr 2008;13:425-432.
Abele-Webster LA, Magill-Evans JE, Pei JR. Sensory processing and ADHD in children with fetal alcohol spectrum disorder. Can J Occup Ther 2012;79:60-63.
Adams JN, Feldman HM, Huffman LC, Loe IM. Sensory processing in preterm preschoolers and its association with executive function. Early Hum Dev 2015;91:227-233.
Baranek GT, Chin YH, Hess LM, Yankee JG, Hatton DD, Hooper SR. Sensory processing correlates of occupational performance in children with fragile X syndrome: preliminary findings. Am J Occup Ther 2002;56:538-546.
Bruni M, Cameron D, Dua S, Noy S. Reported sensory processing of children with Down syndrome. Phys Occup Ther Pediatr 2010;30:280-293.
Pavao SL, Rocha N. Sensory processing disorders in children with cerebral palsy. Infant Behav Dev 2017;46:1-6.
Shimizu VT, Bueno OF, Miranda MC. Sensory processing abilities of children with ADHD. Braz J Phys Ther 2014;18:343-352.
Nieto C, Lopez B, Gandia H. Relationships between atypical sensory processing patterns, maladaptive behaviour and maternal stress in Spanish children with autism spectrum disorder. J Intellect Disabil Res 2017;61:1140-1150.
Siper PM, Kolevzon A, Wang AT, Buxbaum JD, Tavassoli T. A clinician-administered observation and corresponding caregiver interview capturing DSM-5 sensory reactivity symptoms in children with ASD. Autism Res 2017;10:1133-1140.
Van Etten HM, Kaur M, Srinivasan SM, Cohen SJ, Bhat A, Dobkins KR. Increased prevalence of unusual sensory behaviors in infants at risk for, and teens with, autism spectrum disorder. J Autism Dev Disord 2017;47:3431-3445.
Green D, Chandler S, Charman T, Simonoff E, Baird G. Brief report: DSM-5 sensory behaviours in children with and without an autism spectrum disorder. J Autism Dev Disord 2016;46:3597-606.
Brockevelt BL, Nissen R, Schweinle WE, Kurtz E, Larson KJ. A comparison of the Sensory Profile scores of children with autism and an age- and gender-matched sample. S D Med 2013;66:459, 461, 463-465.
Bar-Shalita T, Vatine JJ, Parush S. Sensory modulation disorder: a risk factor for participation in daily life activities. Dev Med Child Neurol 2008;50:932-937.
Baranek GT, David FJ, Poe MD, Stone WL, Watson LR. Sensory Experiences Questionnaire: discriminating sensory features in young children with autism, developmental delays, and typical development. J Child Psychol Psychiatry 2006;47:591-601.
Lin CL, Min YF, Chou LW, Lin CK. Effectiveness of sensory processing strategies on activity level in inclusive preschool classrooms. Neuropsychiatr Dis Treat 2012;8:475-481.
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L. Effectiveness of sensory integration interventions in children with autism spectrum disorders: a pilot study. Am J Occup Ther 2011;65:76-85.
Dunn W. Sensory Profile 2: User's Manual. San Antonio, TX: Psychological Corporation; 2014.
Miller-Kuhaneck H, Henry DA, Glennon TJ, Mu K. Development of the Sensory Processing Measure-School: initial studies of reliability and validity. Am J Occup Ther 2007;61:170-175.
American Psychiatric Association. Neurodevelopmental Disorders. Diagnostic and Statistical Manual of Mental Disorders. DSM Library. Washington, DC: American Psychiatric Association; 2013.
Gioia GA, Isquith PK, Guy SC, Kenworthy L. BRIEF-2: Behavior Rating Inventory of Executive Function. Lutz, FL: Psychological Assessment Resources; 2015.
Goodman R. The Strengths and Difficulties Questionnaire: a research note. J Child Psychol Psychiatry 1997;38:581-586.
Varni JW, Seid M, Kurtin PS. PedsQL™ 4.0: Reliability and Validity of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales in Healthy and Patient Populations. Med Care 2001;39:800-812.
Varni JW, Seid M, Rode CA. The PedsQLTM: measurement model for the Pediatric Quality of Life Inventory. Med Care 1999;37:126-139.
Chang S, Himle MB, Tucker BT, Woods DW, Piacentini J. Initial psychometric properties of a brief parent-report instrument for assessing tic severity in children with chronic tic disorders. Child Fam Behav Ther 2009;31:181-191.
Cohen JW. Statistical Power Analysis for the Behavioural Sciences (2nd ed.). Hillsdale, NJ: Erlbaum; 1998.
IBM Corp. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.; 2017.
O'Hare D, Helmes E, Reece J, Eapen V, McBain K. The differential impact of Tourette's syndrome and comorbid diagnosis on the quality of life and functioning of diagnosed children and adolescents. J Child Adolesc Psychiatr Nurs 2016;29:30-36.
Ganos C, Garrido A, Navalpotro-Gómez I, Ricciardi L, Martino D, Edwards MJ, et al. Premonitory urge to tic in Tourette's is associated with interoceptive awareness. Mov Disord. 2015;30:1198-1202.
Dugas C, Simard MN, Fombonne E, Couture M. Comparison of two tools to assess sensory features in children with autism spectrum disorder. Am J Occup Ther 2018;72:7201195010p1-p9.
Soler N, Hardwick C, Perkes IE, Dossetor D, Bray P, Dale RC. An exploratory study into an adapted use of the Alert Program for tic disorder in children. Australas Psychiatry 2019;27:144-151.