Cerebral blood flow dynamic in foetuses with hypoplastic left heart syndrome: Incremental value of the first segment of the anterior cerebral artery over the middle cerebral artery?
Adult
Anterior Cerebral Artery
/ diagnostic imaging
Blood Flow Velocity
Case-Control Studies
Cerebrovascular Circulation
Female
Humans
Hypoplastic Left Heart Syndrome
/ diagnostic imaging
Infant, Newborn
Middle Cerebral Artery
/ diagnostic imaging
Pregnancy
Pulsatile Flow
Ultrasonography, Doppler
Ultrasonography, Prenatal
Young Adult
Journal
Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
05
03
2019
revised:
30
08
2019
accepted:
06
09
2019
pubmed:
17
9
2019
medline:
9
2
2021
entrez:
17
9
2019
Statut:
ppublish
Résumé
To investigate the blood flow Doppler parameters of the anterior cerebral artery (ACA) in foetuses with hypoplastic left heart syndrome (HLHS). Doppler parameters (peak systolic velocity [PSV], end-diastolic velocity [EDV], time-averaged maximum velocity [TAMXV] and pulsatility index [PI]) and biometric parameters were measured in two anatomical segments of the ACA (S1 and S2) and in the middle cerebral artery (MCA) in 35 HLHS foetuses and 73 gestational age-matched normal foetuses. Correlations between the cerebral artery PIs and head circumference (HC) were assessed. Both EDV and TAMXV of the ACA and MCA in the HLHS group were significantly higher than in the normal group (P < .05). The PI of the ACA and MCA in the HLHS group were significantly lower than in the normal group (P < .05). ACAS1PI and ACAS2PI in the HLHS foetuses with retrograde blood flow in the aortic isthmus (AoI) were significantly lower than those of HLHS foetuses without retrograde blood flow in the AoI (P < .05). ACAS2PI was significantly lower than ACAS1PI in the HLHS foetuses with retrograde blood flow in the AoI (P = .047). The abnormal rates of ACAS1 and ACAS2 were significantly higher than that of the MCA (P < .05) in the HLHS group. The HC and biparietal diameter were significantly lower in the HLHS group than in the control group (P < .05). HC was correlated with the PIs of ACAS1, ACAS2 and the MCA in the HLHS group (P < .05). A redistribution of foetal cerebral blood flow appeared in HLHS, and the measurement of ACA PI might provide early information on brain hypoxia.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
216-222Informations de copyright
© 2019 John Wiley & Sons, Ltd.
Références
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