The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis.
CDKA;1
ASY1
ASY3
PCH2
chromosome axis
Journal
The EMBO journal
ISSN: 1460-2075
Titre abrégé: EMBO J
Pays: England
ID NLM: 8208664
Informations de publication
Date de publication:
03 02 2020
03 02 2020
Historique:
received:
24
01
2019
revised:
02
09
2019
accepted:
04
09
2019
pubmed:
27
9
2019
medline:
8
8
2020
entrez:
27
9
2019
Statut:
ppublish
Résumé
Meiosis is key to sexual reproduction and genetic diversity. Here, we show that the Arabidopsis cyclin-dependent kinase Cdk1/Cdk2 homolog CDKA;1 is an important regulator of meiosis needed for several aspects of meiosis such as chromosome synapsis. We identify the chromosome axis protein ASYNAPTIC 1 (ASY1), the Arabidopsis homolog of Hop1 (homolog pairing 1), essential for synaptonemal complex formation, as a target of CDKA;1. The phosphorylation of ASY1 is required for its recruitment to the chromosome axis via ASYNAPTIC 3 (ASY3), the Arabidopsis reductional division 1 (Red1) homolog, counteracting the disassembly activity of the AAA
Identifiants
pubmed: 31556459
doi: 10.15252/embj.2019101625
pmc: PMC6996576
doi:
Substances chimiques
ASY1 protein, Arabidopsis
0
ASY3 protein, Arabidopsis
0
Arabidopsis Proteins
0
DNA-Binding Proteins
0
CDKA1 protein, Arabidopsis
EC 2.7.11.22
Cyclin-Dependent Kinases
EC 2.7.11.22
Adenosine Triphosphatases
EC 3.6.1.-
PCH2 protein, Arabidopsis
EC 3.6.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e101625Subventions
Organisme : French Government
ID : ANR-10-LABX-0040-SPS
Pays : International
Organisme : University of Hamburg
Pays : International
Informations de copyright
© 2019 The Authors. Published under the terms of the CC BY 4.0 license.
Références
J Biol Chem. 1999 Jan 15;274(3):1783-90
pubmed: 9880561
J Cell Sci. 2001 May;114(Pt 10):1811-20
pubmed: 11329367
PLoS Genet. 2013 May;9(5):e1003508
pubmed: 23671425
Plant Cell. 2010 Nov;22(11):3791-803
pubmed: 21119056
Plant Cell. 2013 Feb;25(2):637-48
pubmed: 23404887
Nat Biotechnol. 2008 Dec;26(12):1367-72
pubmed: 19029910
EMBO J. 2016 Oct 4;35(19):2068-2086
pubmed: 27497297
Nat Commun. 2015 Apr 20;6:6871
pubmed: 25891897
Nature. 2008 Oct 2;455(7213):689-92
pubmed: 18716619
Nat Genet. 2006 Jan;38(1):63-7
pubmed: 16311592
EMBO J. 2020 Jan 2;39(1):e101112
pubmed: 31721251
Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12534-12539
pubmed: 31164422
Annu Rev Genet. 1999;33:603-754
pubmed: 10690419
Development. 2008 Oct;135(20):3389-400
pubmed: 18787066
Nat Commun. 2019 Apr 15;10(1):1755
pubmed: 30988453
Nature. 2003 Oct 23;425(6960):859-64
pubmed: 14574415
Annu Rev Plant Biol. 2015;66:297-327
pubmed: 25494464
Nat Commun. 2018 Oct 1;9(1):4016
pubmed: 30275497
PLoS Genet. 2009 Sep;5(9):e1000654
pubmed: 19763177
Plant Cell. 2009 Nov;21(11):3641-54
pubmed: 19948791
Cell. 2006 Jun 30;125(7):1321-32
pubmed: 16814718
Plant Physiol. 2001 Nov;127(3):1157-66
pubmed: 11706195
Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E44-53
pubmed: 24367111
Nat Genet. 2003 Sep;35(1):25-31
pubmed: 12923533
Plant J. 2012 Apr;70(2):348-56
pubmed: 22098373
Plant Cell. 2011 Dec;23(12):4382-93
pubmed: 22167058
Mol Biol Cell. 2005 Dec;16(12):5804-18
pubmed: 16221890
PLoS Genet. 2009 Oct;5(10):e1000702
pubmed: 19851446
EMBO J. 2002 Jun 17;21(12):3081-95
pubmed: 12065421
Cold Spring Harb Perspect Biol. 2015 May 18;7(6):null
pubmed: 25986558
Elife. 2019 Jan 18;8:
pubmed: 30657449
Genes Cells. 2010 Oct;15(10):1036-50
pubmed: 20825495
Mol Cell. 2016 Dec 1;64(5):940-950
pubmed: 27889449
Genetics. 2006 Aug;173(4):1969-81
pubmed: 16783010
J Cell Sci. 2002 Sep 15;115(Pt 18):3645-55
pubmed: 12186950
Cell. 1990 Apr 6;61(1):73-84
pubmed: 2107981
J Cell Biol. 2015 Nov 23;211(4):745-55
pubmed: 26598612
PLoS Genet. 2012;8(7):e1002865
pubmed: 22844260
Genes Dev. 1998 Nov 15;12(22):3551-63
pubmed: 9832507
Trends Cell Biol. 2013 Jul;23(7):345-56
pubmed: 23566594
PLoS Genet. 2016 Feb 12;12(2):e1005856
pubmed: 26871453
J Cell Sci. 2001 Feb;114(Pt 4):685-93
pubmed: 11171374
J Biol Chem. 2010 Apr 9;285(15):11628-37
pubmed: 20150422
Gene. 2014 Jul 25;545(2):194-7
pubmed: 24814187
Nat Cell Biol. 2009 Nov;11(11):1275-6
pubmed: 19884882
Genetics. 1990 Nov;126(3):563-74
pubmed: 2249756
Plant J. 2018 Jan;93(1):17-33
pubmed: 29078019
Plant Methods. 2014 Oct 15;10(1):33
pubmed: 25337148
Plant Reprod. 2013 Sep;26(3):143-58
pubmed: 23852379
Nature. 2010 Dec 23;468(7327):1074-9
pubmed: 21179163
J Cell Biol. 1997 Mar 10;136(5):957-67
pubmed: 9060462
Mol Cell. 2011 Aug 5;43(3):406-17
pubmed: 21816347
Mol Biotechnol. 2009 May;42(1):14-29
pubmed: 19145493
Plant Methods. 2012 Jun 28;8(1):23
pubmed: 22741569
Nat Genet. 1996 Jul;13(3):336-42
pubmed: 8673133
Bioinformatics. 2010 Apr 1;26(7):966-8
pubmed: 20147306
PLoS Genet. 2013;9(9):e1003787
pubmed: 24086145
Nature. 2007 May 17;447(7142):312-5
pubmed: 17468744
PLoS Genet. 2012 Feb;8(2):e1002507
pubmed: 22319460
Elife. 2019 May 20;8:
pubmed: 31107238
Genes Cells. 1997 Oct;2(10):615-29
pubmed: 9427283
J Cell Sci. 2006 Sep 15;119(Pt 18):3754-63
pubmed: 16940350
J Biol Chem. 2009 Apr 3;284(14):9558-65
pubmed: 19202191
Cell. 2008 Mar 7;132(5):758-70
pubmed: 18329363
Nat Genet. 2012 Mar 11;44(4):467-70
pubmed: 22406643
Annu Rev Cell Dev Biol. 1997;13:261-91
pubmed: 9442875
Protein Expr Purif. 2013 Nov;92(1):54-61
pubmed: 24012791
Dev Cell. 2012 May 15;22(5):1030-40
pubmed: 22595674
Dev Cell. 2014 Nov 24;31(4):487-502
pubmed: 25446517
DNA Repair (Amst). 2009 Sep 2;8(9):983-95
pubmed: 19473888
PLoS Genet. 2015 Jul 16;11(7):e1005372
pubmed: 26182244
PLoS Genet. 2010 Jun 17;6(6):e1000989
pubmed: 20585549
Hum Mol Genet. 2012 Jun 1;21(11):2476-84
pubmed: 22367880
Plant Cell. 2012 May;24(5):2058-70
pubmed: 22589466
Anal Chem. 2003 Feb 1;75(3):663-70
pubmed: 12585499
Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2182-7
pubmed: 24469829
Nature. 2007 Aug 16;448(7155):811-5
pubmed: 17700700
Trends Biochem Sci. 1998 Aug;23(8):284-6
pubmed: 9757827
PLoS Genet. 2012;8(8):e1002847
pubmed: 22879821
Plant Cell. 2007 Mar;19(3):972-85
pubmed: 17369369
Nucleic Acids Res. 2018 Jan 9;46(1):279-292
pubmed: 29186573
Plant Physiol. 2017 Mar;173(3):1530-1542
pubmed: 28108697
Methods Mol Biol. 2013;990:227-34
pubmed: 23559218