Retrospective and Prospective Look at Aflatoxin Research and Development from a Practical Standpoint.
Aflatoxins
/ analysis
Agriculture
/ history
Biomedical Research
/ history
Climate Change
Developing Countries
Food Microbiology
/ history
Global Health
Health Policy
History, 17th Century
History, 19th Century
History, 20th Century
History, Ancient
Humans
Mycotoxicosis
/ diagnosis
Poisons
/ analysis
Prospective Studies
Public Health
/ history
Retrospective Studies
aflatoxins
climatic change
control means
foods and feeds
liver cancer
public health risk
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
27 09 2019
27 09 2019
Historique:
received:
17
08
2019
revised:
24
09
2019
accepted:
26
09
2019
entrez:
2
10
2019
pubmed:
2
10
2019
medline:
11
2
2020
Statut:
epublish
Résumé
Among the array of structurally and toxicologically diverse mycotoxins, aflatoxins have attracted the most interest of scientific research due to their high toxicity and incidence in foods and feeds. Despite the undeniable progress made in various aspects related to aflatoxins, the ultimate goal consisting of reducing the associated public health risks worldwide is far from being reached due to multiplicity of social, political, economic, geographic, climatic, and development factors. However, a reasonable degree of health protection is attained in industrialized countries owing to their scientific, administrative, and financial capacities allowing them to use high-tech agricultural management systems. Less fortunate situations exist in equatorial and sub-equatorial developing countries mainly practicing traditional agriculture managed by smallholders for subsistence, and where the climate is suitable for mould growth and aflatoxin production. This situation worsens due to climatic change producing conditions increasingly suitable for aflatoxigenic mould growth and toxin production. Accordingly, it is difficult to harmonize the regulatory standards of aflatoxins worldwide, which prevents agri-foods of developing countries from accessing the markets of industrialized countries. To tackle the multi-faceted aflatoxin problem, actions should be taken collectively by the international community involving scientific research, technological and social development, environment protection, awareness promotion, etc. International cooperation should foster technology transfer and exchange of pertinent technical information. This review presents the main historical discoveries leading to our present knowledge on aflatoxins and the challenges that should be addressed presently and in the future at various levels to ensure higher health protection for everybody. In short, it aims to elucidate where we come from and where we should go in terms of aflatoxin research/development.
Identifiants
pubmed: 31569703
pii: ijerph16193633
doi: 10.3390/ijerph16193633
pmc: PMC6801849
pii:
doi:
Substances chimiques
Aflatoxins
0
Poisons
0
Types de publication
Historical Article
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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