Effects of 1 year of exercise training versus combined exercise training and weight loss on body composition, low-grade inflammation and lipids in overweight patients with coronary artery disease: a randomized trial.
Adiposity
Aged
Biomarkers
/ blood
C-Reactive Protein
/ metabolism
Caloric Restriction
Coronary Artery Disease
/ blood
Denmark
Dyslipidemias
/ blood
Exercise Therapy
Female
Health Status
Humans
Inflammation
/ blood
Inflammation Mediators
/ blood
Lipids
/ blood
Male
Middle Aged
Obesity
/ blood
Oxygen Consumption
Physical Fitness
Receptors, Urokinase Plasminogen Activator
/ blood
Time Factors
Treatment Outcome
Tumor Necrosis Factor-alpha
/ blood
Weight Loss
Aerobic interval training
Coronary artery disease
Dyslipidaemia
Low-grade inflammation
Secondary prevention
Weight loss
Journal
Cardiovascular diabetology
ISSN: 1475-2840
Titre abrégé: Cardiovasc Diabetol
Pays: England
ID NLM: 101147637
Informations de publication
Date de publication:
01 10 2019
01 10 2019
Historique:
received:
15
06
2019
accepted:
21
09
2019
entrez:
3
10
2019
pubmed:
3
10
2019
medline:
12
5
2020
Statut:
epublish
Résumé
Dyslipidaemia and low-grade inflammation are central in atherogenesis and linked to overweight and physical inactivity. Lifestyle changes are important in secondary prevention of coronary artery disease (CAD). We compared the effects of combined weight loss and interval training with interval training alone on physical fitness, body composition, dyslipidaemia and low-grade inflammation in overweight, sedentary participants with CAD. Seventy CAD patients, BMI 28-40 kg/m Twenty-six (74%) AIT and 29 (83%) LED + AIT participants completed the study. At baseline subject included 43 (78%) men; subjects averages were: age 63 years (6.2), body weight 95.9 kg (12.2) and VO Both interventions were feasible. Both groups obtained improvements in VO
Sections du résumé
BACKGROUND
Dyslipidaemia and low-grade inflammation are central in atherogenesis and linked to overweight and physical inactivity. Lifestyle changes are important in secondary prevention of coronary artery disease (CAD). We compared the effects of combined weight loss and interval training with interval training alone on physical fitness, body composition, dyslipidaemia and low-grade inflammation in overweight, sedentary participants with CAD.
METHODS
Seventy CAD patients, BMI 28-40 kg/m
RESULTS
Twenty-six (74%) AIT and 29 (83%) LED + AIT participants completed the study. At baseline subject included 43 (78%) men; subjects averages were: age 63 years (6.2), body weight 95.9 kg (12.2) and VO
CONCLUSIONS
Both interventions were feasible. Both groups obtained improvements in VO
Identifiants
pubmed: 31575375
doi: 10.1186/s12933-019-0934-x
pii: 10.1186/s12933-019-0934-x
pmc: PMC6774219
doi:
Substances chimiques
Biomarkers
0
Inflammation Mediators
0
Lipids
0
PLAUR protein, human
0
Receptors, Urokinase Plasminogen Activator
0
TNF protein, human
0
Tumor Necrosis Factor-alpha
0
C-Reactive Protein
9007-41-4
Banques de données
ClinicalTrials.gov
['NCT01724567']
Types de publication
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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