Neutralization of insulin by photocleavage under high vacuum.

Insulin / chemistry Ions / chemistry Molecular Structure Peptides / chemistry Photochemical Processes Vacuum

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
25 Oct 2019
Historique:
pubmed: 3 10 2019
medline: 7 11 2019
entrez: 3 10 2019
Statut: ppublish

Résumé

Charge reduction and neutralization of electro-sprayed peptides are realized by selective gas-phase photocleavage of tailored covalent tags. The concept is demonstrated with four model peptides in positive and negative ion modes and tagged insulin as the largest construct.

Identifiants

DOI: 10.1039/c9cc05712a PMID: 31576386
pubmed: 31576386
doi: 10.1039/c9cc05712a
doi:

Substances chimiques

Insulin 0
Ions 0
Peptides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12507-12510

Auteurs

Jonas Schätti (J)

Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.

Moritz Kriegleder (M)

Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.

Maxime Debiossac (M)

Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
ORCID: 0000-0002-0264-2168

Michael Kerschbaum (M)

Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.

Philipp Geyer (P)

Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.

Marcel Mayor (M)

Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch and Institute of Nanotechnology, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany and Lehn Institute of Functional Materials (LIFM), Sun Yat-Sen University (SYSU), XinGangXi Road 135, 510275 Guangzhou, P. R. China.
ORCID: 0000-0002-8094-7813

Markus Arndt (M)

Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna, Austria. markus.arndt@univie.ac.at.
ORCID: 0000-0002-9487-4985

Valentin Köhler (V)

Department of Chemistry, University of Basel, St. Johannsring 19, CH Basel, Switzerland. valentin.koehler@unibas.ch.
ORCID: 0000-0002-7828-423X

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Neutralization of insulin by photocleavage...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Neutralization of insulin by photocleavage...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Neutralization of insulin by photocleavage...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Neutralization of insulin by photocleavage...
questionsmedicales.fr › Phénomènes chimiques › Processus photochimiques › Neutralization of insulin by photocleavage...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Pression atmosphérique › Vide › Neutralization of insulin by photocleavage...