Salvianolic acid A & B: potential cytotoxic polyphenols in battle against cancer via targeting multiple signaling pathways.


Journal

International journal of biological sciences
ISSN: 1449-2288
Titre abrégé: Int J Biol Sci
Pays: Australia
ID NLM: 101235568

Informations de publication

Date de publication:
2019
Historique:
received: 10 06 2019
accepted: 11 07 2019
entrez: 9 10 2019
pubmed: 9 10 2019
medline: 28 4 2020
Statut: epublish

Résumé

Nature has generously offered life-saving therapies to mankind by providing evolutionarily optimized drug-like entities in the form of natural products. These splendid gifts of nature have served as most suitable candidates for anti-cancer drug discovery due to their pleiotropic activity on target molecules. This review aims to provide an update on the natural sources and bioactivities of such gifts from nature, salvianolic acid A & B, which are major bioactive constituents of a traditional Chinses medicinal herb,

Identifiants

pubmed: 31592132
doi: 10.7150/ijbs.37467
pii: ijbsv15p2256
pmc: PMC6775286
doi:

Substances chimiques

Antineoplastic Agents 0
Benzofurans 0
Caffeic Acids 0
Drugs, Chinese Herbal 0
Lactates 0
Polyphenols 0
salvianolic acid A 51622542XO
salvianolic acid B C1GQ844199

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2256-2264

Informations de copyright

© The author(s).

Déclaration de conflit d'intérêts

Competing Interests: The authors have declared that no competing interest exists.

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Auteurs

Tian Qin (T)

The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.

Azhar Rasul (A)

The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Ayesha Sarfraz (A)

Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Iqra Sarfraz (I)

Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Ghulam Hussain (G)

Neurochemicalbiology and Genetics Laboratory (NGL), Department of Physiology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Haseeb Anwar (H)

Neurochemicalbiology and Genetics Laboratory (NGL), Department of Physiology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Ammara Riaz (A)

Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, 38000, Faisalabad, Pakistan.

Sitong Liu (S)

The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
College of Life Sciences, Jilin University, Changchun, 130012, China.

Wei Wei (W)

The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.
Dental Hospital, Jilin University, Changchun 130021, China.

Jiang Li (J)

Dental Hospital, Jilin University, Changchun 130021, China.

Xiaomeng Li (X)

The Key Laboratory of Molecular Epigenetics of MOE, Institute of Genetics and Cytology, Northeast Normal University, Changchun 130024, China.

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Classifications MeSH