Assessing localized dosimetric effects due to unplanned gas cavities during pelvic MR-guided radiotherapy using Monte Carlo simulations.
IGRT
Image-guided radiotherapy
MR-guided radiotherapy
MRgRT
cancer
dose
radiotherapy
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
09
07
2019
revised:
01
10
2019
accepted:
01
10
2019
pubmed:
11
10
2019
medline:
23
4
2020
entrez:
11
10
2019
Statut:
ppublish
Résumé
It has been proposed that beam modulation and opposing beam configurations can cancel effects of the Electron Return Effect (ERE) during MR-guided radiotherapy (MRgRT). However, this may not always be the case for unplanned gas cavities outside of the target in the pelvic region. We evaluate dosimetric effects, including effects in the rectal wall, due to unplanned spherical air cavities during MRgRT. Nine virtual cuboid water phantoms containing spherical air cavities (0.5-7.5 cm diameter) and a reference phantom without air were created. Monte Carlo dose calculations of 7 MV photons under the influence of a 1.5 T transverse magnetic field were produced using Monaco 5.19.02 Treatment Planning System (TPS) (Elekta AB, Stockholm, Sweden). Cavities in the path of a single and multiple beam plans were considered. Dose distributions of phantoms with and without air cavities were compared (ΔD Max(ΔD Unplanned gas cavities in the path of a single beam during pelvic MRgRT with a 1.5 T transverse magnetic field cause dose changes which may impact toxicity in the rectal wall, depending on local dose and fractionation. Effects are reduced but not eliminated with a five-beam plan.
Substances chimiques
Gases
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5807-5815Subventions
Organisme : European Association of National Metrology Institutes
ID : R120635]
Informations de copyright
© 2019 American Association of Physicists in Medicine.
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