VISTA is an acidic pH-selective ligand for PSGL-1.
Animals
Antibodies, Blocking
/ immunology
B7 Antigens
/ antagonists & inhibitors
CD4-Positive T-Lymphocytes
/ cytology
Crystallography, X-Ray
Epitopes, B-Lymphocyte
/ chemistry
Female
Histidine
/ metabolism
Humans
Hydrogen-Ion Concentration
Ligands
Male
Membrane Glycoproteins
/ immunology
Mice
Models, Molecular
Neoplasms
/ drug therapy
Programmed Cell Death 1 Receptor
/ antagonists & inhibitors
Protein Binding
/ drug effects
Protein Domains
T-Lymphocytes
/ cytology
Tumor Microenvironment
/ immunology
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
25
10
2018
accepted:
20
09
2019
entrez:
25
10
2019
pubmed:
28
10
2019
medline:
20
11
2019
Statut:
ppublish
Résumé
Co-inhibitory immune receptors can contribute to T cell dysfunction in patients with cancer
Identifiants
pubmed: 31645726
doi: 10.1038/s41586-019-1674-5
pii: 10.1038/s41586-019-1674-5
doi:
Substances chimiques
Antibodies, Blocking
0
B7 Antigens
0
Epitopes, B-Lymphocyte
0
Ligands
0
Membrane Glycoproteins
0
P-selectin ligand protein
0
Programmed Cell Death 1 Receptor
0
VSIR protein, human
0
Histidine
4QD397987E
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
565-570Références
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