Circulating β cell-specific CD8

Autoimmunity / immunology CD8-Positive T-Lymphocytes / immunology Child Child, Preschool Diabetes Mellitus, Type 1 / blood Female HLA-A24 Antigen / immunology HLA-B Antigens / immunology Histocompatibility Antigens Class I / immunology Humans Infant Insulin / immunology Insulin-Secreting Cells / immunology Male Protein Precursors / immunology Risk Factors
HLA-A*24 HLA-B*39 CD8+ T cells type 1 diabetes

Journal

Clinical and experimental immunology
ISSN: 1365-2249
Titre abrégé: Clin Exp Immunol
Pays: England
ID NLM: 0057202

Informations de publication

Date de publication:
03 2020
Historique:
accepted: 24 10 2019
pubmed: 30 10 2019
medline: 28 7 2020
entrez: 30 10 2019
Statut: ppublish

Résumé

In type 1 diabetes (T1D), autoreactive cytotoxic CD8

Identifiants

DOI: 10.1111/cei.13391 PMID: 31660582 PMC: PMC7008222
pubmed: 31660582
doi: 10.1111/cei.13391
pmc: PMC7008222
doi:

Substances chimiques

HLA-A*24:02 antigen 0
HLA-A24 Antigen 0
HLA-B Antigens 0
Histocompatibility Antigens Class I 0
Insulin 0
Protein Precursors 0
preproinsulin 61116-24-3

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

263-277

Subventions

Organisme : Wellcome Trust
ID : WT100327MA
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom

Informations de copyright

© 2019 British Society for Immunology.

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Auteurs

L Yeo (L)

Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
ORCID: 0000-0002-9638-4920

I Pujol-Autonell (I)

Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.

R Baptista (R)

National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.

M Eichmann (M)

Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.

D Kronenberg-Versteeg (D)

Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.

S Heck (S)

National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.

G Dolton (G)

Division of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.

A K Sewell (AK)

Division of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.

T Härkönen (T)

Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

M-L Mikk (ML)

Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.

J Toppari (J)

Department of Paediatrics, University of Turku and Turku University Hospital, Turku, Finland.
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland.

R Veijola (R)

Department of Paediatrics, PEDEGO Research Unit, Medical Research Centre, Oulu University Hospital and University of Oulu, Oulu, Finland.

M Knip (M)

Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Department of Pediatrics, Tampere University Hospital, Tampere, Finland.
Folkhälsan Research Centre, Helsinki, Finland.

J Ilonen (J)

Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.
Clinical Microbiology, Turku University Hospital, Turku, Finland.

M Peakman (M)

Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
King's Health Partners Institute of Diabetes, Endocrinology and Obesity, London, UK.

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Classifications MeSH

questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Auto-immunité › Circulating β cell-specific CD8
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD8+ › Circulating β cell-specific CD8
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Circulating β cell-specific CD8
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Circulating β cell-specific CD8
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Diabète de type 1 › Circulating β cell-specific CD8
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-A › Antigène HLA-A24 › Circulating β cell-specific CD8
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-B › Circulating β cell-specific CD8
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes d'histocompatibilité de classe I › Circulating β cell-specific CD8
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Circulating β cell-specific CD8
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Circulating β cell-specific CD8
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Circulating β cell-specific CD8
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules entéroendocrines › Cellules à insuline › Circulating β cell-specific CD8
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Précurseurs de protéines › Circulating β cell-specific CD8
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Circulating β cell-specific CD8