Immunological exhaustion and functional profile of CD8
Biomarkers
/ blood
CD8-Positive T-Lymphocytes
/ drug effects
Chagas Cardiomyopathy
/ drug therapy
Chagas Disease
/ drug therapy
Chronic Disease
Costimulatory and Inhibitory T-Cell Receptors
/ metabolism
Cytokines
/ blood
Humans
Nitroimidazoles
/ pharmacology
Programmed Cell Death 1 Receptor
/ blood
Signaling Lymphocytic Activation Molecule Family
/ blood
Trypanocidal Agents
/ pharmacology
Trypanosoma cruzi
Benznidazole treatment
CD8(+) T cell
Chagas disease
Cytokines
Cytotoxic molecules
Inhibitory receptor
Journal
Acta tropica
ISSN: 1873-6254
Titre abrégé: Acta Trop
Pays: Netherlands
ID NLM: 0370374
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
12
07
2019
revised:
21
10
2019
accepted:
23
10
2019
pubmed:
2
11
2019
medline:
16
4
2020
entrez:
1
11
2019
Statut:
ppublish
Résumé
The lack of useful tools for detection the impact of treatment during the follow-up of chronic Chagas disease treated patients difficult the adequate care to the affected population. The objective of this study was to evaluate the functional response of CD8
Identifiants
pubmed: 31669531
pii: S0001-706X(19)30927-1
doi: 10.1016/j.actatropica.2019.105242
pii:
doi:
Substances chimiques
Biomarkers
0
CD244 protein, human
0
Costimulatory and Inhibitory T-Cell Receptors
0
Cytokines
0
Nitroimidazoles
0
Programmed Cell Death 1 Receptor
0
Signaling Lymphocytic Activation Molecule Family
0
Trypanocidal Agents
0
benzonidazole
YC42NRJ1ZD
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105242Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None.