Early sarcomere and metabolic defects in a zebrafish
Acetylcysteine
/ pharmacology
Animals
Animals, Genetically Modified
Antioxidants
/ pharmacology
Arrhythmias, Cardiac
/ drug therapy
Cardiac Conduction System Disease
/ etiology
Cardiomyopathies
/ genetics
Disease Models, Animal
Electrocardiography
Gene Expression Regulation
Homeodomain Proteins
/ genetics
Larva
/ drug effects
Mitochondria, Heart
/ genetics
Sarcomeres
/ genetics
Stress, Physiological
/ genetics
Transcription Factors
/ genetics
Zebrafish
/ genetics
Zebrafish Proteins
/ genetics
cardiac development
cardiac metabolism
cardiomyopathy
transcriptional profiling
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
26 11 2019
26 11 2019
Historique:
pubmed:
11
11
2019
medline:
28
4
2020
entrez:
10
11
2019
Statut:
ppublish
Résumé
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. The major AF susceptibility locus 4q25 establishes long-range interactions with the promoter of
Identifiants
pubmed: 31704768
pii: 1913905116
doi: 10.1073/pnas.1913905116
pmc: PMC6883774
doi:
Substances chimiques
Antioxidants
0
Homeodomain Proteins
0
Pitx2 protein, zebrafish
0
Transcription Factors
0
Zebrafish Proteins
0
pitx2c protein, zebrafish
0
Acetylcysteine
WYQ7N0BPYC
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
24115-24121Déclaration de conflit d'intérêts
The authors declare no competing interest.
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