Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
5-alpha Reductase Inhibitors
/ administration & dosage
Administration, Oral
Administration, Topical
Adult
Aged
Alopecia Areata
/ diagnosis
Biopsy
Cicatrix
/ diagnosis
Dermoscopy
Disease Progression
Drug Therapy, Combination
/ methods
Female
Fibrosis
Follow-Up Studies
Hair Follicle
/ diagnostic imaging
Humans
Hydroxychloroquine
/ administration & dosage
Immunosuppressive Agents
/ administration & dosage
Injections, Subcutaneous
Lichen Planus
/ complications
Male
Middle Aged
Retrospective Studies
Scalp Dermatoses
/ complications
Treatment Outcome
cicatricial alopecia
fibrosing alopecia
fibrosing alopecia in pattern distribution
histopathology
lichen planopilaris
scalp itching
trichoscopy
Journal
Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
08
04
2019
revised:
18
10
2019
accepted:
03
11
2019
pubmed:
11
11
2019
medline:
24
4
2021
entrez:
11
11
2019
Statut:
ppublish
Résumé
Fibrosing alopecia in a pattern distribution and cicatricial pattern hair loss are poorly recognized diffuse variants of lichen planopilaris (LPP). The medical features of 40 patients affected by a diffuse hair thinning associated with a long-lasting history of pruritus and erythema of the scalp and a histopathologic diagnosis of LPP were reviewed. Clinical data, results of trichoscopy and histopathology, response to treatment, and follow-up were analyzed. There were 18 patients diagnosed with fibrosing alopecia in pattern distribution and 2 patients with cicatricial pattern hair loss. A new variant of diffuse LPP, named "lichen planopilaris diffuse pattern," was described in 20 individuals. Low number of cases due to rarity of the diseases. In patients complaining of a long-lasting history of scalp erythema, itching/dysesthesia, and diffuse hair thinning, it is advisable to consider diffuse variants of LPP.
Sections du résumé
BACKGROUND
BACKGROUND
Fibrosing alopecia in a pattern distribution and cicatricial pattern hair loss are poorly recognized diffuse variants of lichen planopilaris (LPP).
OBJECTIVES
OBJECTIVE
The medical features of 40 patients affected by a diffuse hair thinning associated with a long-lasting history of pruritus and erythema of the scalp and a histopathologic diagnosis of LPP were reviewed.
METHODS
METHODS
Clinical data, results of trichoscopy and histopathology, response to treatment, and follow-up were analyzed.
RESULTS
RESULTS
There were 18 patients diagnosed with fibrosing alopecia in pattern distribution and 2 patients with cicatricial pattern hair loss. A new variant of diffuse LPP, named "lichen planopilaris diffuse pattern," was described in 20 individuals.
LIMITATIONS
CONCLUSIONS
Low number of cases due to rarity of the diseases.
CONCLUSION
CONCLUSIONS
In patients complaining of a long-lasting history of scalp erythema, itching/dysesthesia, and diffuse hair thinning, it is advisable to consider diffuse variants of LPP.
Identifiants
pubmed: 31706933
pii: S0190-9622(19)33006-3
doi: 10.1016/j.jaad.2019.11.006
pii:
doi:
Substances chimiques
5-alpha Reductase Inhibitors
0
Immunosuppressive Agents
0
Hydroxychloroquine
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Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1659-1667Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.