Neural motor complexes propagate continuously along the full length of mouse small intestine and colon.
Animals
Cholinergic Antagonists
/ pharmacology
Cholinesterase Inhibitors
/ pharmacology
Colon
/ innervation
Enteric Nervous System
/ drug effects
Female
Ganglionic Blockers
/ pharmacology
In Vitro Techniques
Intestine, Small
/ innervation
Male
Mice, Inbred C57BL
Myoelectric Complex, Migrating
/ drug effects
Peristalsis
/ drug effects
Pressure
Time Factors
colon
motor complex
mouse
neurogenic
small intestine
Journal
American journal of physiology. Gastrointestinal and liver physiology
ISSN: 1522-1547
Titre abrégé: Am J Physiol Gastrointest Liver Physiol
Pays: United States
ID NLM: 100901227
Informations de publication
Date de publication:
01 01 2020
01 01 2020
Historique:
pubmed:
12
11
2019
medline:
6
5
2020
entrez:
12
11
2019
Statut:
ppublish
Résumé
Cyclical propagating waves of muscle contraction have been recorded in isolated small intestine or colon, referred to here as motor complexes (MCs). Small intestinal and colonic MCs are neurogenic, occur at similar frequencies, and propagate orally or aborally. Whether they can be coordinated between the different gut regions is unclear. Motor behavior of whole length mouse intestines, from duodenum to terminal rectum, was recorded by intraluminal multisensor catheter. Small intestinal MCs were recorded in 27/30 preparations, and colonic MCs were recorded in all preparations (
Identifiants
pubmed: 31709829
doi: 10.1152/ajpgi.00185.2019
doi:
Substances chimiques
Cholinergic Antagonists
0
Cholinesterase Inhibitors
0
Ganglionic Blockers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM