Mycobacterial Trehalose 6,6'-Dimycolate-Induced M1-Type Inflammation.


Journal

The American journal of pathology
ISSN: 1525-2191
Titre abrégé: Am J Pathol
Pays: United States
ID NLM: 0370502

Informations de publication

Date de publication:
02 2020
Historique:
received: 12 07 2019
revised: 23 09 2019
accepted: 11 10 2019
pubmed: 18 11 2019
medline: 6 5 2020
entrez: 18 11 2019
Statut: ppublish

Résumé

Murine models of Mycobacterium tuberculosis (Mtb) infection demonstrate progression of M1-like (proinflammatory) and M2-like (anti-inflammatory) macrophage morphology following primary granuloma formation. The Mtb cell wall cording factor, trehalose 6,6'-dimycolate (TDM), is a physiologically relevant and useful molecule for modeling early macrophage-mediated events during establishment of the tuberculosis-induced granuloma pathogenesis. Here, it is shown that TDM is a major driver of the early M1-like macrophage response as seen during initiation of the granulomas of primary pathology. Proinflammatory cytokines tumor necrosis factor-α, IL-1β, IL-6, and IL-12p40 are produced in lung tissue after administration of TDM to mice. Furthermore, CD11b

Identifiants

pubmed: 31734231
pii: S0002-9440(19)30803-X
doi: 10.1016/j.ajpath.2019.10.006
pmc: PMC7013273
pii:
doi:

Substances chimiques

Adjuvants, Immunologic 0
Cord Factors 0
Inflammation Mediators 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

286-294

Subventions

Organisme : NIAID NIH HHS
ID : R41 AI117990
Pays : United States

Informations de copyright

Copyright © 2020 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

Références

J Interferon Cytokine Res. 2004 Jun;24(6):362-71
pubmed: 15212710
mBio. 2013 Jun 18;4(3):e00264-13
pubmed: 23781069
J Immunol. 1982 Nov;129(5):2179-85
pubmed: 6749986
Nat Immunol. 2015 Jan;16(1):57-63
pubmed: 25521685
Am J Respir Crit Care Med. 1994 Feb;149(2 Pt 1):510-8
pubmed: 8306054
PLoS One. 2015 Nov 24;10(11):e0142979
pubmed: 26599209
Immunol Rev. 2011 Mar;240(1):235-51
pubmed: 21349097
Microbiol Spectr. 2014 Oct;2(5):
pubmed: 26104343
Semin Immunol. 2014 Dec;26(6):471-85
pubmed: 25453226
J Immunol. 2014 Oct 1;193(7):3664-75
pubmed: 25156364
J Biol Chem. 2014 Oct 24;289(43):30052-62
pubmed: 25202022
Immun Inflamm Dis. 2017 Dec;5(4):503-514
pubmed: 28722316
Immunity. 2015 Aug 18;43(2):382-93
pubmed: 26287683
PLoS One. 2016 Mar 17;11(3):e0148738
pubmed: 26986986
Microbes Infect. 2007 Jun;9(7):847-54
pubmed: 17533152
Br J Exp Pathol. 1955 Feb;36(1):8-17
pubmed: 14351632
Eur J Immunol. 2015 Aug;45(8):2191-202
pubmed: 26140356
Ann Clin Lab Sci. 1993 Jul-Aug;23(4):256-66
pubmed: 8373130
J Infect. 2015 Apr;70(4):324-34
pubmed: 25455017
Ann Clin Lab Sci. 1997 Sep-Oct;27(5):375-83
pubmed: 9303177
Infect Immun. 1975 Jan;11(1):57-64
pubmed: 1090526
Immunol Rev. 2015 Mar;264(1):74-87
pubmed: 25703553
Infect Immun. 2015 Jan;83(1):324-38
pubmed: 25368116
Infect Immun. 2001 Feb;69(2):810-5
pubmed: 11159972
PLoS One. 2015 Dec 23;10(12):e0145342
pubmed: 26699615
J Leukoc Biol. 2019 Aug;106(2):275-282
pubmed: 30938876
Nat Rev Microbiol. 2007 Jan;5(1):39-47
pubmed: 17160001
Infect Immun. 1994 Feb;62(2):754-6
pubmed: 8300239
Turk J Haematol. 2001 Jun 5;18(2):95-100
pubmed: 27264063
Front Cell Infect Microbiol. 2018 Sep 18;8:327
pubmed: 30283745
Infect Immun. 2004 Dec;72(12):7084-95
pubmed: 15557632
BMC Microbiol. 2017 Aug 23;17(1):185
pubmed: 28835201
Pathog Dis. 2016 Oct;74(7):
pubmed: 27402783
Immunol Rev. 2015 Mar;264(1):220-32
pubmed: 25703562
J Immunol. 2010 Mar 15;184(6):2756-60
pubmed: 20164423
Front Immunol. 2018 Jul 10;9:1593
pubmed: 30042766
J Immunol. 2005 Apr 15;174(8):5007-15
pubmed: 15814731
Tuberculosis (Edinb). 2019 May;116S:S118-S122
pubmed: 31072690
Microbiology. 2002 Jul;148(Pt 7):1991-1998
pubmed: 12101287
Pathog Dis. 2018 Jun 1;76(4):
pubmed: 29762680
Front Microbiol. 2018 May 23;9:1028
pubmed: 29875747
Microbiology. 2007 Oct;153(Pt 10):3360-3369
pubmed: 17906135
Microbiology. 2008 Jun;154(Pt 6):1813-1824
pubmed: 18524936
Int J Tuberc Lung Dis. 2002 Oct;6(10):927-32
pubmed: 12365581
PLoS One. 2015 Jun 19;10(6):e0129744
pubmed: 26091535
PLoS Pathog. 2009 Jun;5(6):e1000474
pubmed: 19521507
Microbes Infect. 2009 Jan;11(1):40-8
pubmed: 19007905
J Exp Med. 2009 Dec 21;206(13):2865-8
pubmed: 20008525
J Interferon Cytokine Res. 2000 Sep;20(9):795-804
pubmed: 11032399
Int J Mol Sci. 2017 Sep 29;18(10):
pubmed: 28961183
Mol Cell. 2000 Apr;5(4):717-27
pubmed: 10882107
Immunity. 2013 May 23;38(5):1050-62
pubmed: 23602766
Clin Dev Immunol. 2012;2012:635451
pubmed: 22666284
Immunobiology. 2013 Apr;218(4):664-73
pubmed: 22921586
Ann Clin Lab Sci. 2006 Autumn;36(4):371-86
pubmed: 17127724
Trends Immunol. 2017 Jan;38(1):66-76
pubmed: 27889398
Nat Immunol. 2007 Jun;8(6):630-8
pubmed: 17450144
Microbiol Immunol. 2001;45(12):801-11
pubmed: 11838897
Am J Pathol. 2016 May;186(5):1221-33
pubmed: 26968340
J Exp Med. 2009 Dec 21;206(13):2879-88
pubmed: 20008526
Nat Methods. 2012 Jul;9(7):671-5
pubmed: 22930834
Semin Immunopathol. 2018 Nov;40(6):577-591
pubmed: 30306257
Front Immunol. 2019 May 24;10:1084
pubmed: 31178859
Cell Host Microbe. 2018 Sep 12;24(3):439-446.e4
pubmed: 30146391
Microbiology. 2003 Aug;149(Pt 8):2049-2059
pubmed: 12904545

Auteurs

Thao K T Nguyen (TKT)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas; The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, Texas.

John d'Aigle (J)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas; The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, Texas.

Luis Chinea (L)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas.

Zainab Niaz (Z)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas.

Robert L Hunter (RL)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas.

Shen-An Hwang (SA)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas.

Jeffrey K Actor (JK)

Department of Pathology and Laboratory Medicine, UTHealth McGovern Medical School, Houston, Texas. Electronic address: jeffrey.k.actor@uth.tmc.edu.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male
Humans Meals Time Factors Female Adult

Classifications MeSH