In vitro antifungal activity of luliconazole against nondermatophytic moulds.
Amphotericin B
/ pharmacology
Antifungal Agents
/ pharmacology
Clotrimazole
/ pharmacology
Fluconazole
/ pharmacology
Fungi
/ classification
Humans
Imidazoles
/ pharmacology
Itraconazole
/ pharmacology
Ketoconazole
/ pharmacology
Miconazole
/ pharmacology
Microbial Sensitivity Tests
Morpholines
/ pharmacology
Sequence Analysis, DNA
Terbinafine
/ pharmacology
Triazoles
/ pharmacology
Voriconazole
/ pharmacology
Neoscytalidium
MIC
antifungal activity
luliconazole
nondermatophyte
Journal
Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835
Informations de publication
Date de publication:
01 Jul 2020
01 Jul 2020
Historique:
received:
06
08
2019
revised:
04
10
2019
accepted:
11
11
2019
pubmed:
24
11
2019
medline:
26
1
2021
entrez:
24
11
2019
Statut:
ppublish
Résumé
In vitro antifungal activity of luliconazole against nondermatophytic moulds causing superficial infections was compared with that of five classes of 12 topical and systemic drugs. The minimum inhibitory concentration (MIC) of the drugs against the genera of Neoscytalidium, Fusarium, Aspergillus, Scedosporium, and Alternaria was measured via modified microdilution method. In results, the nondermatophytic moulds were found to be less susceptible to drugs to which Neoscytalidium spp. and Fusarium spp. were typically drug resistant. However, luliconazole was effective against all the genera tested, including afore-mentioned two species, and had the lowest MICs among the drugs tested.
Identifiants
pubmed: 31758690
pii: 5638893
doi: 10.1093/mmy/myz117
doi:
Substances chimiques
Antifungal Agents
0
Imidazoles
0
Morpholines
0
Triazoles
0
Itraconazole
304NUG5GF4
latoconazole
4E7858311F
Miconazole
7NNO0D7S5M
Amphotericin B
7XU7A7DROE
Fluconazole
8VZV102JFY
amorolfine
AB0BHP2FH0
Clotrimazole
G07GZ97H65
Terbinafine
G7RIW8S0XP
efinaconazole
J82SB7FXWB
Voriconazole
JFU09I87TR
bifonazole
QYJ305Z91O
Ketoconazole
R9400W927I
luliconazole
RE91AN4S8G
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
703-706Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.