Clinical Utility of Diffusion-weighted Whole-body Magnetic Resonance Imaging with Background Body Signal Suppression for Assessing and Monitoring IgG4-related Disease.
Aged
Anti-Inflammatory Agents
/ therapeutic use
Diffusion Magnetic Resonance Imaging
/ methods
Humans
Immunoglobulin G4-Related Disease
/ diagnosis
Magnetic Resonance Imaging
/ methods
Male
Multimodal Imaging
/ methods
Positron Emission Tomography Computed Tomography
/ methods
Prednisolone
/ therapeutic use
Tomography, Spiral Computed
/ methods
Treatment Outcome
Whole Body Imaging
/ methods
DWIBS
IgG4-related disease
MRI
Journal
Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241
Informations de publication
Date de publication:
01 Apr 2020
01 Apr 2020
Historique:
pubmed:
4
12
2019
medline:
22
9
2020
entrez:
3
12
2019
Statut:
ppublish
Résumé
A 77-year-old man with symptoms of chest pain was diagnosed with immunoglobulin G4 (IgG4)-related disease. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) revealed an intense uptake in the submandibular gland, lymph nodes and abdominal aortic wall. Diffusion-weighted imaging with background body signal suppression (DWIBS) revealed signal enhancements at the same location as those of the FDG-PET/CT findings. The DWIBS signal intensity decreased after steroid treatment, so we decreased the steroid dosage. Relapse did not occur. DWIBS makes it possible to adjust the medicine dosage while confirming the therapeutic effects and will likely be a useful method for monitoring IgG4-related disease.
Identifiants
pubmed: 31787698
doi: 10.2169/internalmedicine.3712-19
pmc: PMC7184072
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Prednisolone
9PHQ9Y1OLM
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
951-955Références
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