An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.
Animals
Antigen Presentation
/ genetics
CD8-Positive T-Lymphocytes
/ cytology
Cell Differentiation
Disease Progression
Epigenesis, Genetic
Hepatocyte Nuclear Factor 1-alpha
/ metabolism
Humans
Lymphocytes, Tumor-Infiltrating
/ cytology
Mice
Neoplasms
/ immunology
Stem Cell Niche
/ immunology
Stem Cells
/ cytology
Transcription, Genetic
Tumor Escape
/ genetics
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
11
12
2018
accepted:
13
11
2019
pubmed:
13
12
2019
medline:
28
4
2020
entrez:
13
12
2019
Statut:
ppublish
Résumé
Tumour-infiltrating lymphocytes are associated with a survival benefit in several tumour types and with the response to immunotherapy
Identifiants
pubmed: 31827286
doi: 10.1038/s41586-019-1836-5
pii: 10.1038/s41586-019-1836-5
pmc: PMC7108171
mid: NIHMS1572514
doi:
Substances chimiques
HNF1A protein, human
0
Hepatocyte Nuclear Factor 1-alpha
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
465-470Subventions
Organisme : NCI NIH HHS
ID : 1-R00-CA197891
Pays : United States
Organisme : NIH HHS
ID : P51 OD011132
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA138292
Pays : United States
Organisme : Intramural NIH HHS
ID : Z99 CA999999
Pays : United States
Organisme : NCI NIH HHS
ID : F30 CA243250
Pays : United States
Organisme : NCI NIH HHS
ID : R00 CA197804
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008169
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA113913
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002378
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
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