Rajesh M Valanparambil

Affiliations

Emory Vaccine Center.
Depatment of Microbiology and Immunology, and.

Publications (14)

mTOR regulates T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection.

The Journal of clinical investigation

Avec: Satomi Ando , Charles M Perkins , Yamato Sajiki , Chase Chastain , Rajesh M Valanparambil , Andreas Wieland , William H Hudson , Masao Hashimoto , Suresh S Ramalingam , Gordon J Freeman , Rafi Ahmed , Koichi Araki

Myeloid-Derived Suppressor Cells: The Expanding World of Helminth Modulation of the Immune System.

Frontiers in immunology

Avec: Mary M Stevenson , Rajesh M Valanparambil , Mifong Tam

Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.

Blood cancer discovery

Avec: Maryam I Azeem , Ajay K Nooka , Uma Shanmugasundaram , Narayanaiah Cheedarla , Sayalee Potdar , Renee Julia Manalo , Alberto Moreno , Jeffrey M Switchenko , Suneethamma Cheedarla , Deon Bryant Doxie , Roman Radzievski , Madison Leigh Ellis , Kelly E Manning , Bushra Wali , Rajesh M Valanparambil , Kathryn T Maples , Essence Baymon , Jonathan L Kaufman , Craig C Hofmeister , Nisha S Joseph , Sagar Lonial , John D Roback , Alessandro Sette , Rafi Ahmed , Mehul S Suthar , Andrew S Neish , Madhav V Dhodapkar , Kavita M Dhodapkar

Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies.

Cancer research communications

Avec: Andres Chang , Akil Akhtar , Lilin Lai , Victor M Orellana-Noia , Susanne L Linderman , Ashley A McCook-Veal , Jeffrey M Switchenko , Manpreet Saini , Rajesh M Valanparambil , Kristie A Blum , Pamela B Allen , Mary Jo Lechowicz , Jason T Romancik , Amy Ayers , Alyssa Leal , Colin B O'Leary , Michael C Churnetski , Katelin Baird , Melissa Kives , Jens Wrammert , Ajay K Nooka , Jean L Koff , Madhav V Dhodapkar , Mehul S Suthar , Jonathon B Cohen , Rafi Ahmed

Longitudinal Analysis of the Phenotype, Transcriptional Profile, and Anatomic Location of Memory CD8 T Cell Subsets after Acute Viral Infection.

Journal of virology

Avec: Amanda L Gill , William H Hudson , Rajesh M Valanparambil , Eunseon Ahn , Donald J McGuire , Andreas Wieland , Daniel T McManus , Haydn T Kissick , Rama S Akondy , Rafi Ahmed

Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.

Cancer cell

Avec: Ananda M Rodilla , Rajesh M Valanparambil , Philip C Mack , Chih-Yuan Hsu , Jazz Cagan , Sooyun C Tavolacci , Juan Manuel Carreño , Rachel Brody , Amy Moore , Jennifer C King , Jorge E Gomez , Nicholas Rohs , Christian Rolfo , Paul A Bunn , David E Gerber , John D Minna , Florian Krammer , Suresh S Ramalingam , Adolfo García-Sastre , Yu Shyr , Rafi Ahmed , Fred R Hirsch

CD8

Immunity

Avec: Nataliya Prokhnevska , Maria A Cardenas , Rajesh M Valanparambil , Ewelina Sobierajska , Benjamin G Barwick , Caroline Jansen , Adriana Reyes Moon , Petra Gregorova , Luke delBalzo , Rachel Greenwald , Mehmet Asim Bilen , Mehrdad Alemozaffar , Shreyas Joshi , Cara Cimmino , Christian Larsen , Viraj Master , Martin Sanda , Haydn Kissick

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1

Immunity

Avec: William H Hudson , Julia Gensheimer , Masao Hashimoto , Andreas Wieland , Rajesh M Valanparambil , Peng Li , Jian-Xin Lin , Bogumila T Konieczny , Se Jin Im , Gordon J Freeman , Warren J Leonard , Haydn T Kissick , Rafi Ahmed

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.

Nature

Avec: Caroline S Jansen , Nataliya Prokhnevska , Viraj A Master , Martin G Sanda , Jennifer W Carlisle , Mehmet Asim Bilen , Maria Cardenas , Scott Wilkinson , Ross Lake , Adam G Sowalsky , Rajesh M Valanparambil , William H Hudson , Donald McGuire , Kevin Melnick , Amir I Khan , Kyu Kim , Yun Min Chang , Alice Kim , Christopher P Filson , Mehrdad Alemozaffar , Adeboye O Osunkoya , Patrick Mullane , Carla Ellis , Rama Akondy , Se Jin Im , Alice O Kamphorst , Adriana Reyes , Yuan Liu , Haydn Kissick

Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Rajesh M Valanparambil , Jennifer Carlisle , Susanne L Linderman , Akil Akthar , Ralph Linwood Millett , Lilin Lai , Andres Chang , Ashley A McCook-Veal , Jeffrey Switchenko , Tahseen H Nasti , Manpreet Saini , Andreas Wieland , Kelly E Manning , Madison Ellis , Kathryn M Moore , Stephanie L Foster , Katharine Floyd , Meredith E Davis-Gardner , Venkata-Viswanadh Edara , Mit Patel , Conor Steur , Ajay K Nooka , Felicia Green , Margaret A Johns , Fiona O'Brein , Uma Shanmugasundaram , Veronika I Zarnitsyna , Hasan Ahmed , Lindsay E Nyhoff , Grace Mantus , Michael Garett , Srilatha Edupuganti , Madhusmita Behra , Rustom Antia , Jens Wrammert , Mehul S Suthar , Madhav V Dhodapkar , Suresh Ramalingam , Rafi Ahmed

Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer.

Vaccines

Avec: Philip C Mack , Chih-Yuan Hsu , Ananda M Rodilla , Jorge E Gomez , Jazz Cagan , Yuanhui Huang , Sooyun Tavolacci , Rajesh M Valanparambil , Nicholas Rohs , Rachel Brody , Brittney Nichols , Juan Manuel Carreño , Sheena Bhalla , Christian Rolfo , David E Gerber , Amy Moore , Jennifer C King , Rafi Ahmed , John D Minna , Paul A Bunn , Adolfo García-Sastre , Florian Krammer , Fred R Hirsch , Yu Shyr

Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision.

Immunity

Avec: Kathleen Abadie , Elisa C Clark , Rajesh M Valanparambil , Obinna Ukogu , Wei Yang , Riza M Daza , Kenneth K H Ng , Jumana Fathima , Allan L Wang , Judong Lee , Tahseen H Nasti , Avinash Bhandoola , Armita Nourmohammad , Rafi Ahmed , Jay Shendure , Junyue Cao , Hao Yuan Kueh

BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer.

NPJ vaccines

Avec: Rajesh M Valanparambil , Lilin Lai , Margaret A Johns , Meredith Davis-Gardner , Susanne L Linderman , Tarrant Oliver McPherson , Andres Chang , Akil Akhtar , Estefany L Bocangel Gamarra , Hayley Matia , Ashley A McCook-Veal , Jeffrey Switchenko , Tahseen H Nasti , Felicia Green , Manpreet Saini , Andreas Wieland , Benjamin A Pinsky , Daniel Solis , Madhav V Dhodapkar , Jennifer Carlisle , Suresh Ramalingam , Rafi Ahmed , Mehul S Suthar

Differentiation fate of a stem-like CD4 T cell controls immunity to cancer.

Nature

Avec: Maria A Cardenas , Nataliya Prokhnevska , Ewelina Sobierajska , Petra Gregorova , Christopher B Medina , Rajesh M Valanparambil , Rachel Greenwald , Luke DelBalzo , Mehmet Asim Bilen , Shreyes Joshi , Vikram Naryan , Viraj A Master , Martin G Sanda , Haydn T Kissick

Réseau de co-auteurs

Rafi Ahmed 10 collaborations

Andreas Wieland 5 collaborations

William H Hudson 4 collaborations

Mehul S Suthar 4 collaborations

Madhav V Dhodapkar 4 collaborations

Ajay K Nooka 3 collaborations

Andres Chang 3 collaborations

Lilin Lai 3 collaborations

Susanne L Linderman 3 collaborations

Ashley A McCook-Veal 3 collaborations

Manpreet Saini 3 collaborations

Haydn T Kissick 3 collaborations

Nataliya Prokhnevska 3 collaborations

Mehmet Asim Bilen 3 collaborations

Tahseen H Nasti 3 collaborations

Masao Hashimoto 2 collaborations

Suresh S Ramalingam 2 collaborations

Gordon J Freeman 2 collaborations

Uma Shanmugasundaram 2 collaborations

Jeffrey M Switchenko 2 collaborations

Kelly E Manning 2 collaborations

Akil Akhtar 2 collaborations

Jens Wrammert 2 collaborations

Ananda M Rodilla 2 collaborations

Philip C Mack 2 collaborations

Chih-Yuan Hsu 2 collaborations

Jazz Cagan 2 collaborations

Juan Manuel Carreño 2 collaborations

Rachel Brody 2 collaborations

Amy Moore 2 collaborations

Jennifer C King 2 collaborations

Jorge E Gomez 2 collaborations

Nicholas Rohs 2 collaborations

Christian Rolfo 2 collaborations

Paul A Bunn 2 collaborations

David E Gerber 2 collaborations

John D Minna 2 collaborations

Florian Krammer 2 collaborations

Adolfo García-Sastre 2 collaborations

Yu Shyr 2 collaborations

Fred R Hirsch 2 collaborations

Maria A Cardenas 2 collaborations

Ewelina Sobierajska 2 collaborations

Petra Gregorova 2 collaborations

Rachel Greenwald 2 collaborations

Mehrdad Alemozaffar 2 collaborations

Haydn Kissick 2 collaborations

Se Jin Im 2 collaborations

Viraj A Master 2 collaborations

Martin G Sanda 2 collaborations

Jennifer Carlisle 2 collaborations

Jeffrey Switchenko 2 collaborations

Felicia Green 2 collaborations

Margaret A Johns 2 collaborations

Suresh Ramalingam 2 collaborations

Satomi Ando 1 collaboration

Charles M Perkins 1 collaboration

Yamato Sajiki 1 collaboration

Chase Chastain 1 collaboration

Koichi Araki 1 collaboration

Mary M Stevenson 1 collaboration

Mifong Tam 1 collaboration

Maryam I Azeem 1 collaboration

Narayanaiah Cheedarla 1 collaboration

Sayalee Potdar 1 collaboration

Renee Julia Manalo 1 collaboration

Alberto Moreno 1 collaboration

Suneethamma Cheedarla 1 collaboration

Deon Bryant Doxie 1 collaboration

Roman Radzievski 1 collaboration

Madison Leigh Ellis 1 collaboration

Bushra Wali 1 collaboration

Kathryn T Maples 1 collaboration

Essence Baymon 1 collaboration

Jonathan L Kaufman 1 collaboration

Craig C Hofmeister 1 collaboration

Nisha S Joseph 1 collaboration

Sagar Lonial 1 collaboration

John D Roback 1 collaboration

Alessandro Sette 1 collaboration

Andrew S Neish 1 collaboration

Kavita M Dhodapkar 1 collaboration

Victor M Orellana-Noia 1 collaboration

Kristie A Blum 1 collaboration

Pamela B Allen 1 collaboration

Mary Jo Lechowicz 1 collaboration

Jason T Romancik 1 collaboration

Amy Ayers 1 collaboration

Alyssa Leal 1 collaboration

Colin B O'Leary 1 collaboration

Michael C Churnetski 1 collaboration

Katelin Baird 1 collaboration

Melissa Kives 1 collaboration

Jean L Koff 1 collaboration

Jonathon B Cohen 1 collaboration

Amanda L Gill 1 collaboration

Eunseon Ahn 1 collaboration

Donald J McGuire 1 collaboration

Daniel T McManus 1 collaboration

Rama S Akondy 1 collaboration

Sooyun C Tavolacci 1 collaboration

Benjamin G Barwick 1 collaboration

Caroline Jansen 1 collaboration

Adriana Reyes Moon 1 collaboration

Luke delBalzo 1 collaboration

Shreyas Joshi 1 collaboration

Cara Cimmino 1 collaboration

Christian Larsen 1 collaboration

Viraj Master 1 collaboration

Martin Sanda 1 collaboration

Julia Gensheimer 1 collaboration

Peng Li 1 collaboration

Jian-Xin Lin 1 collaboration

Bogumila T Konieczny 1 collaboration

Warren J Leonard 1 collaboration

Caroline S Jansen 1 collaboration

Jennifer W Carlisle 1 collaboration

Maria Cardenas 1 collaboration

Scott Wilkinson 1 collaboration

Ross Lake 1 collaboration

Adam G Sowalsky 1 collaboration

Donald McGuire 1 collaboration

Kevin Melnick 1 collaboration

Amir I Khan 1 collaboration

Kyu Kim 1 collaboration

Yun Min Chang 1 collaboration

Alice Kim 1 collaboration

Christopher P Filson 1 collaboration

Adeboye O Osunkoya 1 collaboration

Patrick Mullane 1 collaboration

Carla Ellis 1 collaboration

Rama Akondy 1 collaboration

Alice O Kamphorst 1 collaboration

Adriana Reyes 1 collaboration

Yuan Liu 1 collaboration

Akil Akthar 1 collaboration

Ralph Linwood Millett 1 collaboration

Madison Ellis 1 collaboration

Kathryn M Moore 1 collaboration

Stephanie L Foster 1 collaboration

Katharine Floyd 1 collaboration

Meredith E Davis-Gardner 1 collaboration

Venkata-Viswanadh Edara 1 collaboration

Mit Patel 1 collaboration

Conor Steur 1 collaboration

Fiona O'Brein 1 collaboration

Veronika I Zarnitsyna 1 collaboration

Hasan Ahmed 1 collaboration

Lindsay E Nyhoff 1 collaboration

Grace Mantus 1 collaboration

Michael Garett 1 collaboration

Srilatha Edupuganti 1 collaboration

Madhusmita Behra 1 collaboration

Rustom Antia 1 collaboration

Yuanhui Huang 1 collaboration

Sooyun Tavolacci 1 collaboration

Brittney Nichols 1 collaboration

Sheena Bhalla 1 collaboration

Kathleen Abadie 1 collaboration

Elisa C Clark 1 collaboration

Obinna Ukogu 1 collaboration

Wei Yang 1 collaboration

Riza M Daza 1 collaboration

Kenneth K H Ng 1 collaboration

Jumana Fathima 1 collaboration

Allan L Wang 1 collaboration

Judong Lee 1 collaboration

Avinash Bhandoola 1 collaboration

Armita Nourmohammad 1 collaboration

Jay Shendure 1 collaboration

Junyue Cao 1 collaboration

Hao Yuan Kueh 1 collaboration

Meredith Davis-Gardner 1 collaboration

Tarrant Oliver McPherson 1 collaboration

Estefany L Bocangel Gamarra 1 collaboration

Hayley Matia 1 collaboration

Benjamin A Pinsky 1 collaboration

Daniel Solis 1 collaboration

Christopher B Medina 1 collaboration

Luke DelBalzo 1 collaboration

Shreyes Joshi 1 collaboration

Vikram Naryan 1 collaboration