Effect of l-carnitine supplementation on muscle cramps induced by stroke: A case report.
Carnitine
Cerebral infarction
Muscle cramps
Nocturnal leg cramps
Stroke
Journal
Nutrition (Burbank, Los Angeles County, Calif.)
ISSN: 1873-1244
Titre abrégé: Nutrition
Pays: United States
ID NLM: 8802712
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
22
03
2019
revised:
06
09
2019
accepted:
02
11
2019
pubmed:
23
12
2019
medline:
22
1
2021
entrez:
23
12
2019
Statut:
ppublish
Résumé
l-carnitine, a compound responsible for transportation of acyl groups across cell membranes and modulating intracellular acyl-coenzyme A levels, is reported to reduce muscle cramps in patients with liver cirrhosis and diabetes and those on dialysis. A 79-y-old man with right-sided paralysis was admitted to our hospital and diagnosed with cerebral infarction. Nocturnal leg cramps appeared in the affected side and caused sleep disturbance. Supplementation with l-carnitine reduced the number of nocturnal leg cramps and alleviated sleep disturbance. It also plays an important role in nerve protection and treatment for carnitine deficiency. Patients with stroke-induced paralysis experience muscle wasting, which might reduce pooled carnitine in the affected side. This case suggests that stroke may cause localized carnitine deficiency, and l-carnitine supplementation might be effective for muscle cramps induced by stroke. To the best of our knowledge, this is the first case of l-carnitine supplementation for muscle cramps triggered by cerebral infarction.
Identifiants
pubmed: 31864971
pii: S0899-9007(19)30221-7
doi: 10.1016/j.nut.2019.110638
pii:
doi:
Substances chimiques
Carnitine
S7UI8SM58A
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
110638Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.