Performance-Enhanced Non-Enzymatic Glucose Sensor Based on Graphene-Heterostructure.
ALD
PtO
Schottky diode
biosensor
electrochemical
glucometers
glucose
graphene
heterostructure
non-enzymatic
Journal
Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366
Informations de publication
Date de publication:
24 Dec 2019
24 Dec 2019
Historique:
received:
28
11
2019
revised:
16
12
2019
accepted:
20
12
2019
entrez:
28
12
2019
pubmed:
28
12
2019
medline:
30
4
2020
Statut:
epublish
Résumé
Non-enzymatic glucose sensing is a crucial field of study because of the current market demand. This study proposes a novel design of glucose sensor with enhanced selectivity and sensitivity by using graphene Schottky diodes, which is composed of graphene (G)/platinum oxide (PtO)/n-silicon (Si) heterostructure. The sensor was tested with different glucose concentrations and interfering solutions to investigate its sensitivity and selectivity. Different structures of the device were studied by adjusting the platinum oxide film thickness to investigate its catalytic activity. It was found that the film thickness plays a significant role in the efficiency of glucose oxidation and hence in overall device sensitivity. 0.8-2 μA output current was obtained in the case of 4-10 mM with a sensitivity of 0.2 A/mM.cm
Identifiants
pubmed: 31878328
pii: s20010145
doi: 10.3390/s20010145
pmc: PMC6982948
pii:
doi:
Substances chimiques
Oxides
0
platinum oxide
0
Platinum
49DFR088MY
Graphite
7782-42-5
Glucose
IY9XDZ35W2
Silicon
Z4152N8IUI
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : American University in Cairo
ID : Faculty Support Grant
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Mater Sci Eng C Mater Biol Appl. 2014 Aug 1;41:100-18
pubmed: 24907743
Sci Rep. 2018 Jan 12;8(1):571
pubmed: 29330376
Front Bioeng Biotechnol. 2019 Jan 23;7:4
pubmed: 30729107
ACS Appl Mater Interfaces. 2011 Aug;3(8):3049-57
pubmed: 21736289
Nanoscale. 2015 Dec 7;7(45):19099-109
pubmed: 26523705
J Comput Chem. 2009 Apr 30;30(6):934-9
pubmed: 18785153
Nanoscale. 2014 May 7;6(9):4806-11
pubmed: 24663819
Talanta. 2013 Feb 15;105:379-85
pubmed: 23598034
J Pharmacol Exp Ther. 2013 May;345(2):250-9
pubmed: 23487174
Biosens Bioelectron. 2019 Apr 1;130:48-54
pubmed: 30731345
Lancet Diabetes Endocrinol. 2014 Sep;2(9):701-9
pubmed: 24943065
J Comput Chem. 2006 Nov 30;27(15):1787-99
pubmed: 16955487
Biosens Bioelectron. 2016 Aug 15;82:185-94
pubmed: 27085950
Phys Rev Lett. 2008 Jul 11;101(2):026803
pubmed: 18764212
Nano Lett. 2009 Apr;9(4):1472-5
pubmed: 19267449
ACS Appl Mater Interfaces. 2017 May 31;9(21):17663-17680
pubmed: 28485910
ACS Nano. 2014 Dec 23;8(12):11958-65
pubmed: 25415858
Nanoscale. 2015 Jul 21;7(27):11652-9
pubmed: 26098064
Nat Mater. 2016 Nov;15(11):1166-1171
pubmed: 27571451
Biosens Bioelectron. 2011 Aug 15;26(12):4637-48
pubmed: 21683572
Chem Mater. 2013 Mar 12;25(5):761-767
pubmed: 23503321
Cell Metab. 2014 Jun 3;19(6):993-1007
pubmed: 24814481
J Phys Condens Matter. 2009 Sep 30;21(39):395502
pubmed: 21832390