Increased muscle tone and contracture late after ischemic stroke.
muscle spasticity
rehabilitation
stroke
Journal
Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
18
04
2019
revised:
21
10
2019
accepted:
24
11
2019
pubmed:
2
1
2020
medline:
29
12
2020
entrez:
2
1
2020
Statut:
ppublish
Résumé
Systematic studies on increased muscle tone and spasticity late after ischemic stroke, without any selection, are limited. Therefore, we aimed to determine the prevalence of increased muscle tone, classical spasticity and contracture and predictors of increased muscle tone seven years after stroke. Consecutive patients with acute ischemic stroke <70 years of age (n = 411) were recruited to the Sahlgrenska Academy Study on Ischemic Stroke. Symptoms at index stroke were assessed using the Scandinavian Stroke Scale. Seven years after stroke, survivors (n = 358) were invited for follow-up assessments, of whom 292 agreed to participate and 288 contributed data. Muscle tone according to the Modified Ashworth scale, classical spasticity, and contracture was assessed by a neurologist. The associations between increased muscle tone and characteristics at index stroke and recurrent strokes during follow-up were investigated using logistic regression analysis. Increased muscle tone was recognized in 99 participants (34%): 94 (33%) in the upper limbs, and 72 (25%) in the lower limbs. Classical spasticity was found in 51 participants (18%) and contracture in 26 (9%). Age (odds ratio [OR] 1.03 [95% confidence interval [CI] 1.00-1.06]), arm paresis (OR 1.76 [95% CI 1.40-2.2]), aphasia (OR 1.68 [95% CI 1.12-2.51]), and facial palsy (OR 2.12 [95% CI 1.10-4.07]) were independent predictors of increased muscle tone. One-third of patients with ischemic stroke before 70 years of age showed increased muscle tone at 7-year follow-up. Half of them also had classical spasticity. Age, arm paresis, aphasia, and facial palsy at index stroke were predictors of increased muscle tone poststroke.
Sections du résumé
BACKGROUND
Systematic studies on increased muscle tone and spasticity late after ischemic stroke, without any selection, are limited. Therefore, we aimed to determine the prevalence of increased muscle tone, classical spasticity and contracture and predictors of increased muscle tone seven years after stroke.
METHODS
Consecutive patients with acute ischemic stroke <70 years of age (n = 411) were recruited to the Sahlgrenska Academy Study on Ischemic Stroke. Symptoms at index stroke were assessed using the Scandinavian Stroke Scale. Seven years after stroke, survivors (n = 358) were invited for follow-up assessments, of whom 292 agreed to participate and 288 contributed data. Muscle tone according to the Modified Ashworth scale, classical spasticity, and contracture was assessed by a neurologist. The associations between increased muscle tone and characteristics at index stroke and recurrent strokes during follow-up were investigated using logistic regression analysis.
RESULTS
Increased muscle tone was recognized in 99 participants (34%): 94 (33%) in the upper limbs, and 72 (25%) in the lower limbs. Classical spasticity was found in 51 participants (18%) and contracture in 26 (9%). Age (odds ratio [OR] 1.03 [95% confidence interval [CI] 1.00-1.06]), arm paresis (OR 1.76 [95% CI 1.40-2.2]), aphasia (OR 1.68 [95% CI 1.12-2.51]), and facial palsy (OR 2.12 [95% CI 1.10-4.07]) were independent predictors of increased muscle tone.
CONCLUSIONS
One-third of patients with ischemic stroke before 70 years of age showed increased muscle tone at 7-year follow-up. Half of them also had classical spasticity. Age, arm paresis, aphasia, and facial palsy at index stroke were predictors of increased muscle tone poststroke.
Identifiants
pubmed: 31893564
doi: 10.1002/brb3.1509
pmc: PMC7010575
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e01509Subventions
Organisme : The Swedish Stroke Association
Pays : International
Organisme : Renée Eander's Foundation
ID : 2017-01-20
Pays : International
Organisme : The Swedish Research Council
ID : K2014-64X-14605-12-5
Pays : International
Organisme : The Swedish Hypertension Society
Pays : International
Organisme : The Yngve Land Foundation for Neurological Research
Pays : International
Organisme : The Local Research and Development Board for Gothenburg and Södra Bohuslän
ID : VGFOUGSB-669461 and VGFOUGSB-701851
Pays : International
Organisme : The Rune and Ulla Amlöv Foundation for Neurological Research
Pays : International
Organisme : The Swedish State under the ALF agreement
ID : ALFGBG-508331 and ALFGBG-720081
Pays : International
Organisme : The Swedish Heart Lung Foundation
ID : HLF-20160316
Pays : International
Organisme : The John and Brit Wennerström Foundation for Neurological Research
Pays : International
Organisme : The Region Västra Götaland
Pays : International
Informations de copyright
© 2020 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.
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