Activity of two key toxin groups in Australian elapid venoms show a strong correlation to phylogeny but not to diet.


Journal

BMC evolutionary biology
ISSN: 1471-2148
Titre abrégé: BMC Evol Biol
Pays: England
ID NLM: 100966975

Informations de publication

Date de publication:
13 01 2020
Historique:
received: 12 12 2018
accepted: 06 01 2020
entrez: 15 1 2020
pubmed: 15 1 2020
medline: 21 4 2020
Statut: epublish

Résumé

The relative influence of diet and phylogeny on snake venom activity is a poorly understood aspect of snake venom evolution. We measured the activity of two enzyme toxin groups - phospholipase A PLA We have shown that phylogeny is a stronger influence on venom enzyme activity than diet for two of the four major enzyme families present in snake venoms. PLA

Sections du résumé

BACKGROUND
The relative influence of diet and phylogeny on snake venom activity is a poorly understood aspect of snake venom evolution. We measured the activity of two enzyme toxin groups - phospholipase A
RESULTS
PLA
CONCLUSIONS
We have shown that phylogeny is a stronger influence on venom enzyme activity than diet for two of the four major enzyme families present in snake venoms. PLA

Identifiants

pubmed: 31931699
doi: 10.1186/s12862-020-1578-x
pii: 10.1186/s12862-020-1578-x
pmc: PMC6958663
doi:

Substances chimiques

Elapid Venoms 0
Toxins, Biological 0
L-Amino Acid Oxidase EC 1.4.3.2
Phospholipases A2 EC 3.1.1.4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9

Références

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Auteurs

Theo Tasoulis (T)

Clinical Toxicology Research Group, University of Newcastle, Newcastle, New South Wales, 2308, Australia.

Michael S Y Lee (MSY)

Earth Sciences Section, South Australian Museum, North Terrace, Adelaide, S.A, 5000, Australia.
College of Science and Engineering, Flinders University, Bedford Park, S.A, 5042, Australia.

Manon Ziajko (M)

Clinical Toxicology Research Group, University of Newcastle, Newcastle, New South Wales, 2308, Australia.

Nathan Dunstan (N)

Venom Supplies, Tanunda, South Australia, 5352, Australia.

Joanna Sumner (J)

Museums Victoria, Carlton Gardens, Carlton, VIC, 5053, Australia.

Geoffrey K Isbister (GK)

Clinical Toxicology Research Group, University of Newcastle, Newcastle, New South Wales, 2308, Australia. Geoff.isbister@gmail.com.

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Classifications MeSH