A Novel Cyanobacterium Synechococcus elongatus PCC 11802 has Distinct Genomic and Metabolomic Characteristics Compared to its Neighbor PCC 11801.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
13 01 2020
Historique:
received: 16 09 2019
accepted: 20 12 2019
entrez: 15 1 2020
pubmed: 15 1 2020
medline: 13 11 2020
Statut: epublish

Résumé

Cyanobacteria, a group of photosynthetic prokaryotes, are attractive hosts for biotechnological applications. It is envisaged that future biorefineries will deploy engineered cyanobacteria for the conversion of carbon dioxide to useful chemicals via light-driven, endergonic reactions. Fast-growing, genetically amenable, and stress-tolerant cyanobacteria are desirable as chassis for such applications. The recently reported strains such as Synechococcus elongatus UTEX 2973 and PCC 11801 hold promise, but additional strains may be needed for the ongoing efforts of metabolic engineering. Here, we report a novel, fast-growing, and naturally transformable cyanobacterium, S. elongatus PCC 11802, that shares 97% genome identity with its closest neighbor S. elongatus PCC 11801. The new isolate has a doubling time of 2.8 h at 1% CO

Identifiants

pubmed: 31932622
doi: 10.1038/s41598-019-57051-0
pii: 10.1038/s41598-019-57051-0
pmc: PMC6957532
doi:

Substances chimiques

Bacterial Proteins 0
Carbon Dioxide 142M471B3J

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

191

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Auteurs

Damini Jaiswal (D)

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Annesha Sengupta (A)

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Shinjinee Sengupta (S)

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.
DBT-PAN IIT Centre for Bioenergy, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Swati Madhu (S)

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India.

Himadri B Pakrasi (HB)

Department of Biology, Washington University, St. Louis, MO, 63130, USA.
Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, MO, 63130, USA.

Pramod P Wangikar (PP)

Department of Chemical Engineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India. wangikar@iitb.ac.in.
DBT-PAN IIT Centre for Bioenergy, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India. wangikar@iitb.ac.in.
Wadhwani Research Centre for Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, 400076, India. wangikar@iitb.ac.in.

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Classifications MeSH