Efficient whole-cell catalysis for 5-aminovalerate production from L-lysine by using engineered Escherichia coli with ethanol pretreatment.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
22 01 2020
22 01 2020
Historique:
received:
04
10
2019
accepted:
31
12
2019
entrez:
24
1
2020
pubmed:
24
1
2020
medline:
20
11
2020
Statut:
epublish
Résumé
Microorganisms can utilize biomass to produce valuable chemicals, showing sustainable, renewable and economic advantages compared with traditional chemical synthesis. As a potential five-carbon platform polymer monomer, 5-aminovalerate has been widely used in industrial fields such as clothes and disposable goods. Here we establish an efficient whole-cell catalysis for 5-aminovalerate production with ethanol pretreatment. In this study, the metabolic pathway from L-lysine to 5-aminovalerate was constructed at the cellular level by introducing L-lysine α-oxidase. The newly produced H
Identifiants
pubmed: 31969619
doi: 10.1038/s41598-020-57752-x
pii: 10.1038/s41598-020-57752-x
pmc: PMC6976619
doi:
Substances chimiques
Amino Acids, Neutral
0
Ethanol
3K9958V90M
5-aminovaleric acid
660-88-8
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
990Références
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