Impaired Frontal Brain Activity in Patients With Heart Failure Assessed by Near-Infrared Spectroscopy.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
04 02 2020
Historique:
entrez: 25 1 2020
pubmed: 25 1 2020
medline: 22 12 2020
Statut: ppublish

Résumé

Background The prevalence of depression and/or anxiety disorders is reported to be higher in patients with heart failure (HF) than in the general population, and patients with HF also have coexisting cognitive problems. Recently, the development of near-infrared spectroscopy (NIRS) has enabled noninvasive measurements of regional cerebral blood volume and brain activity, in terms of cerebral oxyhemoglobin in the cerebral cortex, with a high time resolution. The aim of the current study was to determine the associations between frontal brain activity and depressive symptoms, anxiety status, and cognitive function in patients with HF. Methods and Results We measured and compared frontal brain activity determined by NIRS during a verbal fluency task in patients with HF (n=35) and control subjects (n=28). The Center for Epidemiologic Studies Depression Scale for assessment of depressive symptoms, State-Trait Anxiety Inventory for assessment of anxiety status, Mini-Mental State Examination for assessment of cognitive function, and NIRS were simultaneously conducted. NIRS showed that frontal brain activity was significantly lower in the HF group than in the control subjects (28.5 versus 88.0 mM·mm;

Identifiants

pubmed: 31973606
doi: 10.1161/JAHA.119.014564
pmc: PMC7033895
doi:

Substances chimiques

Oxyhemoglobins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e014564

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Auteurs

Yasuhiro Ichijo (Y)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

Soichi Kono (S)

Department of Neuropsychiatry Fukushima Medical University Fukushima Japan.

Akiomi Yoshihisa (A)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

Tomofumi Misaka (T)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

Takashi Kaneshiro (T)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

Masayoshi Oikawa (M)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

Itaru Miura (I)

Department of Neuropsychiatry Fukushima Medical University Fukushima Japan.

Hirooki Yabe (H)

Department of Neuropsychiatry Fukushima Medical University Fukushima Japan.

Yasuchika Takeishi (Y)

Department of Cardiovascular Medicine Fukushima Medical University Fukushima Japan.

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Classifications MeSH