Gold Nanoparticle Aggregation-Induced Quantitative Photothermal Biosensing Using a Thermometer: A Simple and Universal Biosensing Platform.


Journal

Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536

Informations de publication

Date de publication:
04 02 2020
Historique:
pubmed: 25 1 2020
medline: 29 12 2020
entrez: 25 1 2020
Statut: ppublish

Résumé

A simple, low-cost, and universal gold nanoparticle (AuNP) aggregation-induced photothermal biosensing platform has been developed for the first time and applied for the visual quantitative genetic detection using a common thermometer. By exploiting the photothermal effect of target-induced gold nanoparticle aggregation, visual quantitative biochemical analysis can be achieved by simply recording temperature signals using a common thermometer. Compared to conventional genetic testing methods, it is label- and amplification-free and can be completed in 40 min without the aid of any advanced analytical instruments.

Identifiants

pubmed: 31977184
doi: 10.1021/acs.analchem.9b04996
doi:

Substances chimiques

DNA Probes 0
DNA, Bacterial 0
Gold 7440-57-5

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

2739-2747

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI107415
Pays : United States
Organisme : NIGMS NIH HHS
ID : SC2 GM105584
Pays : United States

Auteurs

Wan Zhou (W)

Department of Chemistry and Biochemistry , University of Texas at El Paso , 500 West University Avenue , El Paso , Texas 79968 , United States.

Kaiqiang Hu (K)

Department of Chemistry and Biochemistry , University of Texas at El Paso , 500 West University Avenue , El Paso , Texas 79968 , United States.
College of Chemistry and Chemical Engineering , Qingdao University , Qingdao , 266071 , PR China.

Sharon Kwee (S)

Department of Biomedical and Chemical Engineering , University of Texas at San Antonio , One UTSA Circle , San Antonio , Texas 78249 , United States.

Liang Tang (L)

Department of Biomedical and Chemical Engineering , University of Texas at San Antonio , One UTSA Circle , San Antonio , Texas 78249 , United States.

Zonghua Wang (Z)

College of Chemistry and Chemical Engineering , Qingdao University , Qingdao , 266071 , PR China.

Jianfei Xia (J)

College of Chemistry and Chemical Engineering , Qingdao University , Qingdao , 266071 , PR China.

XiuJun Li (X)

Department of Chemistry and Biochemistry , University of Texas at El Paso , 500 West University Avenue , El Paso , Texas 79968 , United States.
Biomedical Engineering, Border Biomedical Research Center , University of Texas at El Paso , 500 West University Avenue , El Paso , Texas 79968 , United States.
Environmental Science and Engineering , University of Texas at El Paso , 500 West University Avenue , El Paso , Texas 79968 , United States.

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Classifications MeSH