Ingenane and jatrophane diterpenoids from Euphorbia kansui and their antiproliferative effects.
DU145 cell lines
Diterpenoid
Euphorbia kansui
Euphorbiaceae
HepG2 cell lines
Ingenane
Jatrophane
MCF-7 cell lines
Journal
Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
27
08
2019
revised:
30
12
2019
accepted:
03
01
2020
pubmed:
28
1
2020
medline:
4
3
2020
entrez:
28
1
2020
Statut:
ppublish
Résumé
In this study, fourteen ingenane-type and nine jatrophane-type diterpenoids were isolated from Euphorbia kansui, including seven undescribed compounds. Kansuingenol A-C have the 6,7-vicinal diol moiety, and Kansuijatrophanol A and B possess the 11,12-vicinal diol moiety, both of which are rarely reported. 3,4-(Methylenedioxy) cinnamyl moiety was found for the first time in jatrophane-type diterpenoids, as shown in Kansuijatrophanol C and D. The absolute configurations of seven undescribed compounds have been analyzed and assigned by the modified Mosher's method, Mo
Identifiants
pubmed: 31986448
pii: S0031-9422(19)30829-5
doi: 10.1016/j.phytochem.2020.112257
pii:
doi:
Substances chimiques
Diterpenes
0
ingenane
0
jatrophane
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112257Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.