Higher incidence of retinopathy of prematurity in extremely preterm infants associated with improved survival rates.
borderline viability
preterm delivery
preterm infants
retinopathy of prematurity
Journal
Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
15
09
2019
revised:
23
01
2020
accepted:
24
01
2020
pubmed:
29
1
2020
medline:
15
5
2021
entrez:
29
1
2020
Statut:
ppublish
Résumé
This study assessed possible reasons for the increasing incidence of retinopathy of prematurity (ROP) since mid-2015 at our institution. Retrospective analysis of all preterm infants born July 2013 to June 2017 with a gestational age (GA) <29 completed weeks admitted to the neonatal intensive care unit at the University Hospital Zurich during the first 28 days of life. The primary outcome measures were severest ROP stage. Statistical analysis was performed using generalised additive models in R. During the study period, survival increased in extremely preterm infants. Significant predictors for severest ROP stage were GA, days of mechanical ventilation and multiple gestation (P = .0322). A composite of severe comorbidities had no significant effect on severest ROP stage. GA was identified as the only significant risk factor the for severest ROP stage (P = .0045). Increased survival rate of extremely preterm infants was associated with an increased incidence of ROP at our institution. Despite the increase, the incidence is still very low compared with other countries. No other additive factors were identified.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2033-2039Informations de copyright
© 2020 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
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