Phylogenetic diversity of
Orientia tsutsugamushi
phylogenetic analysis
polymerase chain reaction
scrub typhus
Journal
Indian journal of medical microbiology
ISSN: 1998-3646
Titre abrégé: Indian J Med Microbiol
Pays: United States
ID NLM: 8700903
Informations de publication
Date de publication:
Historique:
entrez:
1
2
2020
pubmed:
1
2
2020
medline:
2
6
2020
Statut:
ppublish
Résumé
Scrub typhus has re-emerged as an important cause of acute febrile illness in India. There is a dearth of information on strain diversity of Orientia tsutsugamushi from Karnataka, India, hence the present study sought to address this issue. One hundred clinically suspected cases of scrub typhus/rickettsiosis (as per the DHR-ICMR guidelines) were included. Nested-polymerase chain reaction (PCR) for 56-kDa gene and phylogenetic analysis was performed. PCR was positive in 22 cases and phylogenetic analysis showed the presence of different strains, with predominance of clustering (57%) with Gilliam-type for the first time in Karnataka. Knowledge of genetic diversity has implications in development of diagnostics and vaccine.
Identifiants
pubmed: 32003348
pii: IndianJMedMicrobiol_2019_37_3_438_272347
doi: 10.4103/ijmm.IJMM_19_267
doi:
Substances chimiques
DNA, Bacterial
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
438-441Déclaration de conflit d'intérêts
None