Ultrasound, shear-wave elastography, and magnetic resonance imaging in native liver survivor patients with biliary atresia after Kasai portoenterostomy: correlation with medical outcome after treatment.


Journal

Acta radiologica (Stockholm, Sweden : 1987)
ISSN: 1600-0455
Titre abrégé: Acta Radiol
Pays: England
ID NLM: 8706123

Informations de publication

Date de publication:
Oct 2020
Historique:
pubmed: 6 2 2020
medline: 27 10 2020
entrez: 4 2 2020
Statut: ppublish

Résumé

Biliary atresia (BA) is a rare obliterative cholangiopathy and Kasai portoenterostomy (KP) represents its first-line treatment; clinical and laboratory parameters together with abdominal ultrasound (US) are usually performed during the follow-up. Shear-wave elastography (SWE) is able to evaluate liver parenchyma stiffness; magnetic resonance imaging (MRI) has also been proposed to study these patients. To correlate US, SWE, and MRI imaging findings with medical outcome in patients with BA who are native liver survivors after KP. We retrospectively enrolled 24 patients. They were divided in two groups based on "ideal" (n = 15) or "non-ideal" (n = 9) medical outcome. US, SWE, and MRI exams were analyzed qualitatively and quantitatively for imaging signs suggestive of chronic liver disease (CLD). Significant differences were found in terms of liver surface ( US, SWE, and MRI findings correlate with the medical outcome in native liver survivor patients with BA treated with KP.

Sections du résumé

BACKGROUND BACKGROUND
Biliary atresia (BA) is a rare obliterative cholangiopathy and Kasai portoenterostomy (KP) represents its first-line treatment; clinical and laboratory parameters together with abdominal ultrasound (US) are usually performed during the follow-up. Shear-wave elastography (SWE) is able to evaluate liver parenchyma stiffness; magnetic resonance imaging (MRI) has also been proposed to study these patients.
PURPOSE OBJECTIVE
To correlate US, SWE, and MRI imaging findings with medical outcome in patients with BA who are native liver survivors after KP.
MATERIAL AND METHODS METHODS
We retrospectively enrolled 24 patients. They were divided in two groups based on "ideal" (n = 15) or "non-ideal" (n = 9) medical outcome. US, SWE, and MRI exams were analyzed qualitatively and quantitatively for imaging signs suggestive of chronic liver disease (CLD).
RESULTS RESULTS
Significant differences were found in terms of liver surface (
CONCLUSION CONCLUSIONS
US, SWE, and MRI findings correlate with the medical outcome in native liver survivor patients with BA treated with KP.

Identifiants

pubmed: 32008344
doi: 10.1177/0284185120902379
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1300-1308

Auteurs

Martina Caruso (M)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

Renato Cuocolo (R)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

Fabiola Di Dato (F)

Department of Translational Medical Sciences, University of Naples "Federico II," Naples, Italy.

Carmine Mollica (C)

Institute of Bio-Structures and Bio-Imaging of the National Research Council (CNR), Naples, Italy.

Gianfranco Vallone (G)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

Valeria Romeo (V)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

Mario Petretta (M)

Department of Translational Medical Sciences, University of Naples "Federico II," Naples, Italy.

Raffaele Liuzzi (R)

Institute of Bio-Structures and Bio-Imaging of the National Research Council (CNR), Naples, Italy.

Pier Paolo Mainenti (PP)

Institute of Bio-Structures and Bio-Imaging of the National Research Council (CNR), Naples, Italy.

Raffaele Iorio (R)

Department of Translational Medical Sciences, University of Naples "Federico II," Naples, Italy.

Arturo Brunetti (A)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

Simone Maurea (S)

Department of Advanced Biomedical Sciences, University of Naples "Federico II," Naples, Italy.

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Classifications MeSH