Brucellosis associated with stillbirth in a bottlenose dolphin in Australia.
Brucella
abortion
dolphin
marine
stillbirth
Journal
Australian veterinary journal
ISSN: 1751-0813
Titre abrégé: Aust Vet J
Pays: England
ID NLM: 0370616
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
24
05
2019
revised:
10
10
2019
accepted:
15
11
2019
pubmed:
8
2
2020
medline:
2
7
2020
entrez:
8
2
2020
Statut:
ppublish
Résumé
A captive adult female bottlenose dolphin presented with stillbirth. The placenta appeared oedematous. No other gross lesions were evident in the placenta or the stillborn calf. Histopathology revealed mild multifocal placentitis and foetal encephalitis. Brucella sp. was isolated from lung, liver, spleen and kidney. Sequence and phylogenetic analysis demonstrated this organism to be most similar to Brucella ceti sequence type (ST) 27. Brucella sp. DNA was detected in formalin-fixed paraffin-embedded placenta and brain by real-time PCR using primers targeting the IS711 gene. Immunohistochemical staining revealed Brucella sp. antigen in placental inflammation. This is the first report of isolation of Brucella sp. from a marine mammal in the Southern Hemisphere and the first report of marine Brucella-associated disease in Australia.
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
92-95Informations de copyright
© 2020 Australian Veterinary Association.
Références
OIE World Organisation for Animal Health. Brucellosis. Chapter 3.1.4. In: Manual of diagnostic tests and vaccines for terrestrial animals. OIE, 2019 Available at https://www.oie.int/standard-setting/terrestrial-manual/access-online/. Accessed August 2019.
Ewalt DR, Payeur JB, Martin BM et al. Characteristics of a Brucella species from a bottlenose dolphin (Tursiops truncatus). J Vet Diagn Invest 1994;6:448-452.
Ross HM, Foster G, Reid RJ et al. Brucella species infection in sea-mammals. Vet Rec 1994;134:359.
Dawson CE, Stubberfield EJ, Perrett LJ et al. Phenotypic and molecular characterization of Brucella isolates from marine mammals. BMC Microbiol 2008;8:224.
Whatmore AM, Dawson C, Muchowski J et al. Characterisation of North American Brucella isolates from marine mammals. PLoS One 2017;12:e0184758.
Hernandez-Mora G, Palacios-Alfaro JD, Gonzalez-Barriontos R Wildlife reservoirs of brucellosis: Brucella in aquatic environments. Rev Sci Tech Off Int Epiz 2013;32:89-103.
Foster G, Osterman BJ, Godfroid J et al. Brucella ceti sp. nov. and Brucella pinnipedialis sp. nov. for Brucella strains with cetaceans and seals as their preferred hosts. Int J Syst Evol Microbiol 2007;57:2688-2693.
Olsen SC, Palmer MV Advancement of knowledge of Brucella over the past 50 years. Vet Pathol 2014;51:1076-1089.
Miller WG, Adams LG, Ficht TA et al. Brucella-induced abortions and infection in bottlenose dolphins (Tursiops truncates). J Zoo Wildlife Med 1999;30:100-110.
Nymmo IH, Tryland M, Godfroid J A review of Brucella infection in marine mammals, with special emphasis on Brucella pinnipedialis in the hooded seal (Cystophora cristata). Vet Res 2011;42:93.
Duncan CG, Tiller R, Mathis D et al. Brucella placentitis and seroprevalence in northern fur seals (Callorhinus ursinus) of the Pribilof Islands, Alaska. J Vet Diagn Invest 2014;26:507-512.
Foster G, MacMillan AP, Godfroid J et al. A review of Brucella sp. infection of sea mammals with particular emphasis on isolates from Scotland. Vet Microbiol 2002;90:563-580.
Dawson CE Anti-Brucella antibodies in pinnipeds of Australia. Microbiol Aust 2005;26:87-89.
Abalos PP, Blank HO, Torres ND et al. Brucella infection in marine mammals in Antarctica. Vet Rec 2009;164:250.
Buckle K, Roe WD, Howe L et al. Brucellosis in endangered Hector's dolphins (Cephalorhynchus hectori). Vet Pathol 2017;54:838-845.
Lopez-Goni I, Garcia-Yoldi D, Marin CM et al. Evaluation of a multiplex PCR assay (Bruceladder) for molecular typing of all Brucella species, including the vaccine strains. J Clin Microbiol 2008;46:3484-3487.
Gardner SN, Hall BG When whole-genome alignments just won't work: kSNP v2 software for alignment-free SNP discovery and phylogenetics of hundreds of microbiobial genomes. PLoS One 2013;8:e81760.
Hinić V, Brodard I, Thomann A et al. Novel identification and differentiation of Brucella melitensis, B. abortus, B. suis, B. ovis, B. canis, and B. neotamae suitable for both conventional and real-time PCR systems. J Microbiol Methods 2008;75:375-378.
Schlafer DH, Foster RA. Female genital system. In: Maxie MG, editor. Jubb, Kennedy and Palmer's pathology of domestic animals. 6th edn. 3. Elsevier, St Louis, 2016;402-406.
Guzman-Verri C, Gonzales-Barrientos R, Hernandez-Mora G et al. Brucella ceti and brucellosis in cetaceans. Front Cell Infect Microbiol 2012;2:3.
Moore SJ, Radunz B, Glanville RJ Lessons learned during the successful eradication of bovine tuberculosis from Australia. Vet Rec 2015;177:224-232.