Immunogenetics in stem cell donor registry work: The DKMS example (Part 2).
CMV
DKMS
HLA
KIR
MICA/MICB
donor registry
unrelated hematopoietic stem cell transplantation
Journal
International journal of immunogenetics
ISSN: 1744-313X
Titre abrégé: Int J Immunogenet
Pays: England
ID NLM: 101232337
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
02
12
2019
revised:
08
01
2020
accepted:
20
01
2020
pubmed:
9
2
2020
medline:
9
10
2020
entrez:
9
2
2020
Statut:
ppublish
Résumé
DKMS is a leading stem cell donor registry with more than 9 million donors. Donor registry activities share many touch points with topics from immunogenetics or population genetics. In this two-part review article, we deal with these aspects of donor registry work by using the example of DKMS. In the second part of the review, we focus on donor typing of non-HLA genes, the impact of donor age, gender and CMV serostatus on donation probabilities, the identification of novel HLA, KIR and MIC alleles by high-throughput donor typing, the activities of the Collaborative Biobank and pharmacogenetics in the donor registry context.
Identifiants
pubmed: 32034894
doi: 10.1111/iji.12479
pmc: PMC7079094
doi:
Substances chimiques
HLA Antigens
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
139-148Informations de copyright
© 2020 The Authors. International Journal of Immunogenetics . Published by John Wiley & Sons Ltd.
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