Comparative Evaluation of Combinatory Interaction between Endocannabinoid System Compounds and Poly-L-lysine against


Journal

BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173

Informations de publication

Date de publication:
2020
Historique:
received: 05 09 2019
revised: 09 12 2019
accepted: 11 01 2020
entrez: 21 2 2020
pubmed: 23 2 2020
medline: 1 12 2020
Statut: epublish

Résumé

Endocannabinoid/endocannabinoid-like (EC/EC-like) are natural endogenous compounds which have been found to affect MRSA pathogenicity. Our previous studies showed that EC/EC-like was able to impair staphylococcal biofilm formation and maintenance as well as to alter biofilm-associated virulence factors. In the present study, we investigated the combinatory effect of the selected EC/EC-like with a natural antimicrobial agent, poly-L-lysine, on cariogenic bacteria

Identifiants

pubmed: 32076613
doi: 10.1155/2020/7258380
pmc: PMC7013284
doi:

Substances chimiques

Anti-Infective Agents 0
Arachidonic Acids 0
Drug Combinations 0
Endocannabinoids 0
Oleic Acids 0
Polyunsaturated Alkamides 0
oleoylethanolamide 1HI5J9N8E6
Polylysine 25104-18-1
anandamide UR5G69TJKH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7258380

Informations de copyright

Copyright © 2020 Mark Feldman et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest regarding the publication of this paper.

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Auteurs

Mark Feldman (M)

Biofilm Research Laboratory, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Ronit Sionov (R)

Biofilm Research Laboratory, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Reem Smoum (R)

The Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel.

Raphael Mechoulam (R)

The Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel.

Isaac Ginsburg (I)

Biofilm Research Laboratory, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

Doron Steinberg (D)

Biofilm Research Laboratory, Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.

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Classifications MeSH