Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply.
Animals
Aspartic Acid
/ metabolism
Brain
/ metabolism
Calcium
/ metabolism
Calcium Channels
/ deficiency
Cytosol
/ metabolism
Glutamic Acid
/ chemistry
Heart
/ physiology
Malates
/ chemistry
Membrane Potential, Mitochondrial
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria
/ metabolism
Myocardium
/ metabolism
Oxidative Phosphorylation
Pyruvic Acid
/ metabolism
Rats
Substrate Specificity
Synaptosomes
/ metabolism
OXPHOS control
bioenergetics
calcium
cytosolic calcium
fibroblasts
isolated working rat heart
malate-aspartate shuttle
mitochondria
mitochondrial calcium uniporter
mouse
respiratory chain
synaptosomes
thymocytes
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
03 04 2020
03 04 2020
Historique:
received:
14
11
2019
revised:
19
02
2020
pubmed:
26
2
2020
medline:
30
12
2020
entrez:
26
2
2020
Statut:
ppublish
Résumé
Mitochondrial oxidative phosphorylation (OXPHOS) and cellular workload are tightly balanced by the key cellular regulator, calcium (Ca
Identifiants
pubmed: 32094224
pii: S0021-9258(17)48706-0
doi: 10.1074/jbc.RA119.011902
pmc: PMC7135991
doi:
Substances chimiques
Calcium Channels
0
Malates
0
mitochondrial calcium uniporter
0
Aspartic Acid
30KYC7MIAI
Glutamic Acid
3KX376GY7L
Pyruvic Acid
8558G7RUTR
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4383-4397Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2020 Szibor et al.
Références
Nat Genet. 2014 Feb;46(2):188-93
pubmed: 24336167
Mol Cell Biochem. 1997 Sep;174(1-2):143-8
pubmed: 9309679
Nat Commun. 2015 Jan 20;6:6081
pubmed: 25603276
Pediatr Res. 1995 Aug;38(2):221-7
pubmed: 7478820
J Biol Chem. 2004 Feb 6;279(6):4127-35
pubmed: 14625276
Nat Cell Biol. 2013 Dec;15(12):1464-72
pubmed: 24212091
Arch Biochem Biophys. 2012 Feb 15;518(2):157-63
pubmed: 22239987
Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H297-304
pubmed: 18487432
Prog Biophys Mol Biol. 2017 May;125:1-23
pubmed: 27939921
Mol Cell Biochem. 1998 Mar;180(1-2):153-61
pubmed: 9546642
Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9129-34
pubmed: 26153425
FEBS Lett. 1986 Apr 21;199(2):222-6
pubmed: 3084295
JIMD Rep. 2014;14:77-85
pubmed: 24515575
J Mol Cell Cardiol. 2002 Oct;34(10):1259-71
pubmed: 12392982
J Physiol. 2020 Apr;598(7):1307-1326
pubmed: 30218574
J Biol Chem. 2008 Nov 7;283(45):30715-24
pubmed: 18606820
Biochem J. 2012 May 1;443(3):747-55
pubmed: 22295911
Eur J Biochem. 1974 Feb 15;42(1):89-95
pubmed: 4830198
Biophys Chem. 2007 Sep;129(2-3):93-110
pubmed: 17566629
Am J Physiol. 1996 May;270(5 Pt 2):H1607-15
pubmed: 8928865
Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):595-606
pubmed: 20385096
Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1018-27
pubmed: 20144582
EMBO J. 2001 Sep 17;20(18):5060-9
pubmed: 11566871
Biochem Pharmacol. 2006 Feb 14;71(4):399-407
pubmed: 16368075
Eur J Neurosci. 2000 Feb;12(2):571-6
pubmed: 10712636
J Biol Chem. 2002 May 31;277(22):19289-94
pubmed: 11897791
Cell Rep. 2015 Jul 7;12(1):15-22
pubmed: 26119742
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4388-4393
pubmed: 28396416
J Biol Chem. 2009 Mar 13;284(11):7091-9
pubmed: 19129175
Neurobiol Learn Mem. 2015 Apr;120:52-60
pubmed: 25724412
J Biol Chem. 1985 Mar 25;260(6):3440-50
pubmed: 3838314
Biochim Biophys Acta. 1987 Sep 14;930(2):173-8
pubmed: 3620514
J Neurochem. 2017 Jul;142(1):132-139
pubmed: 28429368
J Cereb Blood Flow Metab. 1987 Dec;7(6):752-8
pubmed: 3693430
N Engl J Med. 2009 Jul 30;361(5):489-95
pubmed: 19641205
Biochim Biophys Acta. 2016 Oct;1863(10):2394-412
pubmed: 27132995
Annu Rev Physiol. 1990;52:451-66
pubmed: 2184763
Respir Physiol. 2001 Nov 15;128(3):277-97
pubmed: 11718759
J Neurosci. 2013 Aug 28;33(35):13957-71, 13971a
pubmed: 23986233
J Neurochem. 1990 Aug;55(2):698-707
pubmed: 2164576
Biochem Biophys Res Commun. 2003 May 16;304(4):643-9
pubmed: 12727202
Physiol Rev. 2007 Jan;87(1):29-67
pubmed: 17237342
J Biol Chem. 2018 Oct 5;293(40):15652-15663
pubmed: 30154242
Basic Res Cardiol. 2009 Sep;104(5):547-57
pubmed: 19294446
IUBMB Life. 2013 Mar;65(3):180-90
pubmed: 23401251
Int J Mol Sci. 2019 Sep 10;20(18):
pubmed: 31510000
J Cereb Blood Flow Metab. 2017 Aug;37(8):3027-3041
pubmed: 27909264
J Mol Cell Cardiol. 2015 Aug;85:178-82
pubmed: 26057074
Neuron. 2003 Apr 24;38(2):253-63
pubmed: 12718859
Mol Cell. 2016 Oct 6;64(1):148-162
pubmed: 27642048
Physiol Rev. 1990 Apr;70(2):391-425
pubmed: 2157230
Front Behav Neurosci. 2015 Mar 20;9:58
pubmed: 25852506
Mol Neurobiol. 2016 Sep;53(7):4728-44
pubmed: 26319560
Cell Rep. 2015 Jul 7;12(1):23-34
pubmed: 26119731
Sci Signal. 2019 Apr 30;12(579):
pubmed: 31040260