Extracellular loops matter - subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae.

Amino Acid Transport Systems, Basic / analysis Computational Biology Kinetics Lysine / metabolism Models, Molecular Saccharomyces cerevisiae / chemistry Saccharomyces cerevisiae Proteins / analysis
APC superfamily amino acid loop membrane transport yeast

Journal

The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646

Informations de publication

Date de publication:
10 2020
Historique:
received: 20 12 2019
revised: 05 02 2020
accepted: 24 02 2020
pubmed: 26 2 2020
medline: 18 5 2021
entrez: 26 2 2020
Statut: ppublish

Résumé

Yeast amino acid transporters of the APC superfamily are responsible for the proton motive force-driven uptake of amino acids into the cell, which for most secondary transporters is a reversible process. The l-lysine proton symporter Lyp1 of Saccharomyces cerevisiae is special in that the Michaelis constant from out-to-in transport (

Identifiants

DOI: 10.1111/febs.15262 PMID: 32096906 PMC: PMC7687128
pubmed: 32096906
doi: 10.1111/febs.15262
pmc: PMC7687128
doi:

Substances chimiques

Amino Acid Transport Systems, Basic 0
LYP1 protein, S cerevisiae 0
Saccharomyces cerevisiae Proteins 0
Lysine K3Z4F929H6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4401-4414

Informations de copyright

© 2020 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

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Auteurs

Joury S Van't Klooster (JS)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Frans Bianchi (F)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Ruben B Doorn (RB)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Mirco Lorenzon (M)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Jarnick H Lusseveld (JH)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Christiaan M Punter (CM)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

Bert Poolman (B)

Department of Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.
ORCID: 0000-0002-1455-531X

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Systèmes de transport d'acides aminés › Systèmes de transport d'acides aminés basiques › Extracellular loops matter - subcellular...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › Extracellular loops matter - subcellular...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Extracellular loops matter - subcellular...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Lysine › Extracellular loops matter - subcellular...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › Extracellular loops matter - subcellular...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › Extracellular loops matter - subcellular...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Protéines de Saccharomyces cerevisiae › Extracellular loops matter - subcellular...