In situ metabolite and lipid analysis of GluN2D
Bioanalytical methods
Imaging
Mass spectrometry
Journal
Analytical and bioanalytical chemistry
ISSN: 1618-2650
Titre abrégé: Anal Bioanal Chem
Pays: Germany
ID NLM: 101134327
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
10
12
2019
accepted:
31
01
2020
revised:
27
01
2020
pubmed:
29
2
2020
medline:
30
4
2021
entrez:
29
2
2020
Statut:
ppublish
Résumé
The N-methyl-D-aspartate (NMDA) receptor is a crucial mediator of pathological glutamate-driven excitotoxicity and subsequent neuronal death in acute ischemic stroke. Although the roles of the NMDAR's composite GluN2A-C subunits have been investigated in this phenomenon, the relative importance of the GluN2D subunit has yet to be evaluated. Herein, GluN2D
Identifiants
pubmed: 32107573
doi: 10.1007/s00216-020-02477-z
pii: 10.1007/s00216-020-02477-z
pmc: PMC7483268
mid: NIHMS1568185
doi:
Substances chimiques
Grin2d protein, mouse
0
Lipids
0
Receptors, N-Methyl-D-Aspartate
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6275-6285Subventions
Organisme : NIA NIH HHS
ID : R21 AG062144
Pays : United States
Organisme : NIH HHS
ID : S10 OD018507
Pays : United States
Organisme : NIGMS NIH HHS
ID : S10 OD018507
Pays : United States
Organisme : NIA NIH HHS
ID : R21-AG062144
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM110406
Pays : United States
Références
Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci. 2013;14:383–400.
pubmed: 23686171
Nakazawa K, McHugh TJ, Wilson MA, Tonegawa S. NMDA receptors, place cells and hippocampal spatial memory. Nat Rev Neurosci. 2004;5:361–72.
pubmed: 15100719
Dingledine R, Borges K, Bowie D, Traynelis SF. The glutamate receptor ion channels. Pharmacol Rev. 1999;51:7–61.
pubmed: 10049997
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, et al. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev. 2010;62:405–96.
pubmed: 20716669
pmcid: 2964903
Cheriyan J, Balsara RD, Hansen KB, Casetellino FJ. Pharmacology of triheteromeric N-methyl-d-aspartate receptors. Neurosci Lett. 2016;617:240–6.
pubmed: 26917100
pmcid: 5312704
Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron. 1994;12:529–40.
pubmed: 7512349
Cull-Candy SG, Leszkiewicz DN. Role of distinct NMDA receptor subtypes at central synapses. Science STKE. 2004;re16.
Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature. 1994;368:144–7.
pubmed: 8139656
Gray JA, Shi Y, Usui H, During MJ, Sakimura K, Nicoll RA. Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron. 2011;71:1085–101.
pubmed: 21943605
pmcid: 3183990
Holmes A, Zhou N, Donahue DL, Balsara R, Castellino FJ. A deficiency of the GluN2C subunit of the N-methyl-D-aspartate receptor is neuroprotective in a mouse model of ischemic stroke. Biochem Biophys Res Commun. 2018;495:136–44.
pubmed: 29101031
Dudley E. MALDI profiling and applications in medicine. Adv Exp Med Biol. 2019;1140:27–43.
pubmed: 31347040
Ahmen M, Broeck G, Baggerman G, Schildermans K, Pauwels P, Van Craenenbroeck AH, et al. Next-generation protein analysis in the pathology department. J Clin Pathol. 2019. https://doi.org/10.1136/jclinpath-2019-205864 .
Berghmans E, Van Raemdonck G, Schildermans K, Willems H, Boonen K, Maes E, et al. MALDI mass spectrometry imaging linked with top-down proteomics as a tool to study the non-small-cell lung cancer tumor microenvironment. Methods and Protocols. 2019;2:44.
pmcid: 6632162
Andrews WT, Skube SB, Hummon AB. Magnetic bead-based peptide extraction methodology for tissue imaging. Analyst. 2017;143:133–40.
pubmed: 29119981
pmcid: 5734995
Mallah K, Quanico J, Raffo-Romero A, Cardon T, Aboulouard S, Devos D, et al. Matrix-assisted laser desorption/ionization-mass spectrometry imaging of lipids in experimental model of traumatic brain injury detecting acylcaritines as injury related markers. Anal Chem. 2019. https://doi.org/10.1021/acs.analchem.9b02633 .
Tobias F, Olson MT, Cologna SM. Mass spectrometry imaging of lipids: untargeted consensus spectra reveal spatial distributions in Niemann-Pick disease type C1. J Lipid Res. 2018;12:2446–55.
Liu X, Flinders C, Mumenthaler SM, Hummon AB. MALDI mass spectrometry imaging for evaluation of therapeutics in colorectal tumor organoids. J Am Soc Mass Spectrom. 2018;29:516–26.
pubmed: 29209911
Liu X, Hummon AB. Chemical imaging of platinum-based drugs and their metabolites. Sci Rep. 2016. https://doi.org/10.1038/srep38507 .
Eveque-Mourroux MR, Emans PJ, Zautsen RRM, Boonen A, Heeren RMA, Cilero-Pastor B. Spatially resolved endogenous improved metabolite detection in human osteoarthritis cartilage by matrix assisted laser desorption ionization mass spectrometry imaging. Analyst. 2019. https://doi.org/10.1039/c9an00944b .
Chughtai K, Heeren RMA. Mass spectrometric imaging for biomedical tissue analysis. Chem Rev. 2011;110:3237–77.
Stoeckli M, Chaurand P, Hallahan DE, Caprioli RM. Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat Med. 2001;7:493–6.
pubmed: 11283679
Palmer A, Phapale P, Chernyavsky I, Lavigne R, Fay D, Tarasov A, et al. FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry. Nat Methods. 2016;14:57–60.
pubmed: 27842059
Alexandrov T, Ovchnnikova K, Palmer AJ, Kovalev V, Tarasov A, Stuart L, Nigmetzianov R, Fay D. METASPACE: A community-populated knowledge base of spatial metabolomes in health and disease. BioRxiv. 2019. https://doi.org/10.1101/539478 .
Ellis SR, Paine MRL, Eijkel GB, Pauling JK, Husen P, Jervelund MW, et al. Automated, parallel mass spectrometry imaging and structural identification of lipids. Nat Methods. 2018;5:515–8.
Vaysse PM, Heeren RMA, Porta T, Balluff B. Mass spectrometry imaging for clinical research-latest developments, applications, and current limitations. Analyst. 2017;142:2690–712.
pubmed: 28642940
Gemperline E, Horn HA, DeLaney K, Currie CR, Li L. Imaging with mass spectrometry of bacteria on the exoskeleton of fungus-growing ants. ACS Chem Biol. 2017;12(8):1980–5.
pubmed: 28617577
pmcid: 6314843
Duenas ME, Essner JJ, Lee YJ. 3D MALDI mass spectrometry imaging of a single cell: spatial mapping of lipids in the embryonic development of zebrafish. Sci Rep. 2017;7:14946.
pubmed: 29097697
pmcid: 5668422
Summer LW, Amberg A, Barrett D, Beale MH, Beger R, Daykin CA, et al. Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics. 2007;3(3):211–21.
Falkenburger BH, Jensen JB, Dickson EJ, Suh BC, Hille B. Phosphoinositides: lipid regulators of membrane proteins. J Physiol. 2010;588:3179–85.
pubmed: 20519312
pmcid: 2976013
Heuser D, Guggenberger H. Ionic changes in brain ischemia and alterations produced by drugs. Br J Anesthesia. 1985;57(1):22–33.
White BC, Wiegenstein JG, Winegar CD. Brain ischemia and anoxia: mechanisms of injury. JAMA. 1984;251:158–690.
Farber JL, Chien KR, Mittnacht S Jr. Myocardial ischemia: the pathogenesis of irreversible cell injury in ischemia. Am J Pathol. 1981;102(2):271–81.
pubmed: 7008623
pmcid: 1903688
Blunt JW, DeLuca HF. The synthesis of 25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3. Biochemistry. 1969;8(2):671–5.
pubmed: 4307413
Kopic S, Geibel JP. Gastric acid, calcium absorption, and their impact of bone health. Physiol Rev. 2013;93(1):189–268.
pubmed: 23303909
Sturkie PD. Hormonal Regulation of Calcium Metabolism. Basic Physiology. New York, NY: Springer-Verlag New York Incorporated; 1981. p. 414–8.
Borah M, Dhar S, Gogoi DM, Ruram AA. Association of serum calcium levels with infarct size in acute ischemic stroke: observations from northeast India. J Neurosci Rural Pract. 2016;7(S1):S41–5.
pubmed: 28163502
pmcid: 5244059
Canning P, Kenny BA, Prise V, Glenn J, Sarker MH, Hudson N, et al. Lipoprotein-associated phospholipase A2 (Lp-PLA2) as a therapeutic target to prevent retinal vasopermeability during diabetes. Proc Natl Acad Sci U S A. 2016;113(26):7213–8.
pubmed: 27298369
pmcid: 4932924
Law SH, Chan ML, Marathe GK, Parveen F, Chen CH, Ke LY. An updated review of lysophosphatidylcholine metabolism in human diseases. Int J Mol. 2019;20(5):1149.
Zhou F, Liu Y, Huang Q, Zhou J. Relation between lipoprotein-associated phospholipase A2 mass and incident ischemic stroke severity. Neurol Sci. 2018;39(9):1591–6.
pubmed: 29938341
Wang Y, Hu S, Ren L, Lan T, Cai J, Li C. Lp-PLA2 as a risk factor of early neurological deterioration in acute ischemic stroke with TOAST type of large arterial atherosclerosis. Neurol Res. 2019;41(1):1–8.
pubmed: 30296199
Ding CY, Cai HP, Ge HL, Yu LH, Lin YX, Kang DZ. Assessment of lipoprotein-associated phospholipase A2 level and its changes in the early stages as predictors of delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg. 2019:1–7.
Suzuki J, Fujii T, Imao T, Ishihara K, Kuba H, Nagata S. Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013;288(19):13305–16.
pubmed: 23532839
pmcid: 3650369
Bull RK, Jevons S, Barton PG. Complexes of prothrombin with calcium ions and phospholipids. J Biol Chem. 1972;247(9):2747–54.
pubmed: 4623559
Vallabhapurapu SD, Blanco VM, Sulaiman MK, Vallabhapurapu SL, Chu Z, Franco RS, Qi X. Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium. Oncotarget. 2015;6(33):34375–88. https://doi.org/10.18632/oncotarget.6045 .
Martin-Molina A, Rodriguez-Beas C, Faraudo J. Effect of calcium and magnesium on phosphatidylserine membranes: experiments and all-atomic simulations. Biophys J. 2012;102(9):2095–103.
pubmed: 22824273
pmcid: 3341548
Aussel C, Pelassy C, Mary D, Breittmayer JP, Cousin JL, Rossi B. Calcium-dependent regulation of phosphatidylserine synthesis in control and activated Jurkat T cells. J Lipid Mediat Cell Signal. 1991;3(3):267–81.
Zinrajh D, Horl G, Jurgens G, Marc J, Sok M, Cerne C. Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival. Oncol Lett. 2014;7(6):2175–9.
pubmed: 24932311
pmcid: 4049682
Muralikrishna Adibhatla R, Hatcher JF, Larsen EC, Chen X, Tsao FHC. CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke. J Biol Chem. 2005;281:6718–25.
Nishida A, Emoto K, Shimizu M, Uozumi T, Yamawaki S. Brain ischemia decreases phosphatidylcholine-phospholipase D but not phosphatidylinositol-phospholipase C in rats. Stroke. 1994;25(6):1247–51.
pubmed: 8202988
Sabogal-Guaqueta AM, Villamil-Ortiz JG, Arias-Londono JD, Cardona-Gomez GP. Inverse phosphatidylcholine/phosphatidylinositol levels as peripheral biomarkers and phosphatidylcholine/lysophosphoethanolamine-phosphatidylserine as hippocampal indicator of postischemic cognitive impairment in rats. Front Neurosci. 2018;21. https://doi.org/10.3389/fnins.2018.00989 .
Mousavi SA, Khorvash F, Hoseini T. The efficacy of citroline in the treatment of ischemic stroke and primary hypertensive intracereal hemorrhage; a review article. ARYA Atherosclerosis. 2010;6(3):122–5.
Moto A, Hirashima Y, Endo S, Takaku A. Changes in lipid metabolites and enzymes in rat brain due to ischemia and recirculation. Mol Chem Neuropathol. 1991;14(1):35–51.
pubmed: 1910356
Hattori T, Nishimura Y, Sakai N, Yamada H, Kameyama Y, Nozawa Y. Effects of pentobarbital on brain lipid metabolism during global ischemia. Neurol Surg. 1986;38(6):585–91.
Matthys E, Patel Y, Kreisberg J, Stewart JH, Venkatachalam M. Lipid alterations induced by renal ischemia: pathogenic factor in membrane damage. Kidney Int. 1984;26(2):153–61.
pubmed: 6503134
Sun GY, Lu FL, Lin SE, Ko MR. Decapitation ischemia-induced release of free fatty acids in mouse brain. Relationship with diacylglycerols and lysophospholipids. Mol Chem Neuropathol. 1992;17(1):39–50.
pubmed: 1388450
van der Veen JN, Kennelly JP, Wan S, Vance JE, Vance DE, Jacobs RL. The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. Biochim Biophys Acta Biomembr. 2017;1859(9):1558–72.
pubmed: 28411170
Nilanjana M, Kagan VE, Tyurin VA, Das DK. Redistribution of phosphatidylethanolamine and phosphatidylserine precedes reperfusion-induced apoptosis. Am J Physiol Heart Circ Physiol. 1998:H242–8.
Kawai H, Chaudhry F, Shekhar A, Petrov A, Nakahara T, Tanimoto T, et al. Molecular imaging of apoptosis in ischemia reperfusion injury with radiolabeled duramycin targeting phosphatidylethanolamine. Effective target uptake and reduced nontarget organ radioation burden. J Am Coll Cardiol Img. 2018;11(12). https://doi.org/10.1016/j.jcmg.2017.11.037 .
Schabitz WR, Giuffrida A, Berger C, Aschoff A, Schwaninger M, Schwab S, et al. Release of fatty acid amides in a patient with hemispheric stroke, a microdialysis study. Stroke. 2002;33:2112–4.
pubmed: 12154273
Post JA, Bivelt JJ, Verkleij AJ. Phosphatidylethanolamine and sarcolemmal damage during ischemia or metabolic inhibition of heart myocytes. Am J Physiol Heart Circ Physiol. 1995;268(2):H773–80.
Hirabayashi T, Larson TJ, Dowan W. Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: purification by substrate affinity chromatography on cytidine 5′-diphospho-1,2-diacyl-sn-glycerol sepharose. Biochemistry. 1976;15(24):5205–11.
pubmed: 793612
Morita SY, Terada T. Enzymatic measurement of phosphadiylglycerol and cardiolipin in cultured cells and mitochondria. Sci Rep. 2015;5. https://doi.org/10.1038/srep11737 .
Gebert N, Joshi AS, Kutik S, Becker T, McKenzie M, Guan XL, et al. Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol. 2009;19(24):2133–9.
pubmed: 19962311
pmcid: 4329980
Osman C, Haag M, Wieland FT, Brugger B, Langer T. A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J. 2010;29(12):1976–87.
pubmed: 20485265
pmcid: 2892375
Gross A, Yin XM, Wang K, Wei MC, Jockel J, Milliman C, et al. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem. 1999;274(2):1156–63.
pubmed: 9873064
Orrenius S, Zhivotovsky B. Cardiolipin oxidation sets cytochrome c free. Nat Chem Biol. 2005;1(4):188–9.
pubmed: 16408030
Choi SY, Gonzalvez F, Jenkins GM, Slominanny C, Chretien D, Arnoult D, et al. Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis. Cell Death Differ. 2007;14:597–606.
pubmed: 16888643