Use of next generation sequencing technologies for the diagnosis and epidemiology of infectious diseases.
Uso de las tecnologías de secuenciación masiva para el diagnóstico y epidemiología de enfermedades infecciosas.
Diagnosis
Diagnóstico
Epidemiology
Epidemiología
Genoma
Genome
Next generation sequencing
Resistance
Resistencias
Secuenciación masiva
Vigilance
Vigilancia
Journal
Enfermedades infecciosas y microbiologia clinica (English ed.)
ISSN: 2529-993X
Titre abrégé: Enferm Infecc Microbiol Clin (Engl Ed)
Pays: Spain
ID NLM: 101777541
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
entrez:
1
3
2020
pubmed:
1
3
2020
medline:
30
7
2021
Statut:
ppublish
Résumé
For the first time, next generation sequencing technologies provide access to genomic information at a price and scale that allow their implementation in routine clinical practice and epidemiology. While there are still many obstacles to their implementation, there are also multiple examples of their major advantages compared with previous methods. Their main advantage is that a single determination allows epidemiological information on the causative microorganism to be obtained simultaneously, as well as its resistance profile, although these advantages vary according to the pathogen under study. This review discusses several examples of the clinical and epidemiological use of next generation sequencing applied to complete genomes and microbiomes and reflects on its future in clinical practice.
Identifiants
pubmed: 32111363
pii: S0213-005X(20)30036-7
doi: 10.1016/j.eimc.2020.02.006
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
32-38Informations de copyright
Copyright © 2020. Publicado por Elsevier España, S.L.U.