The challenges of pharmacoepidemiology of orphan drugs in rare diseases.
Electronic health records
Orphan drug
Pharmacoepidemiology
Pharmacovigilance
Rare disease
Journal
Therapie
ISSN: 1958-5578
Titre abrégé: Therapie
Pays: France
ID NLM: 0420544
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
25
09
2019
accepted:
22
10
2019
pubmed:
14
3
2020
medline:
20
2
2021
entrez:
14
3
2020
Statut:
ppublish
Résumé
Large electronic health records database available at a national level offer great opportunity for research in rare diseases and orphan drugs. Methods and data used in pharmacoepidemiology present a great potential for epidemiology, drug utilization studies, drug safety, drug effectiveness and pharmacoeconomics. This review presents the different sources of data in Europe, with a special focus on the French situation, with the recent implementation of SNDS (système national des données de santé [French national health data wharehouse]). Some examples are given. Development of rigorous and innovative methods must be encouraged in the future.
Identifiants
pubmed: 32164974
pii: S0040-5957(20)30018-4
doi: 10.1016/j.therap.2020.02.013
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
215-220Informations de copyright
Copyright © 2020 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.