Genetic counseling for cystic fibrosis: A basic model with new challenges.


Journal

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
ISSN: 1769-664X
Titre abrégé: Arch Pediatr
Pays: France
ID NLM: 9421356

Informations de publication

Date de publication:
Feb 2020
Historique:
entrez: 17 3 2020
pubmed: 17 3 2020
medline: 23 12 2020
Statut: ppublish

Résumé

While the goals of genetic counseling for cystic fibrosis - delivering relevant information on the risk of recurrence and nondirectional support of couples at risk in their reproductive choices - have not changed fundamentally, the practice has evolved considerably in the last decade, growing more complex to face new challenges but also proving more effective. Many factors have contributed to this evolution: technical progress in the exploration of the genome (new generation sequencing) and in reproductive medicine, but also societal developments promoting access to genetic information and the professionalization of genetic counselors in France. The prospect of expanded pre-conception screening of at-risk couples makes genetic counselors major actors not only in medical care centers, but also in modern society by contributing to genetic education among citizens. © 2020 French Society of Pediatrics. Published by Elsevier Masson SAS. All rights reserved.

Identifiants

pubmed: 32172934
pii: S0929-693X(20)30048-8
doi: 10.1016/S0929-693X(20)30048-8
pii:
doi:

Substances chimiques

DNA 9007-49-2

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

eS30-eS34

Informations de copyright

© 2020 Elsevier Masson SAS. Tous droits réservés.

Auteurs

E Bieth (E)

Génétique Médicale, CHU Toulouse, France. Electronic address: bieth.e@chu-toulouse.fr.

J Nectoux (J)

Service de génétique et biologie moléculaires, CHU Paris Centre - Hôpital Cochin, Site Cochin, Paris, France.

A Girardet (A)

Génétique Moléculaire, CHU Montpellier, France.

N Gruchy (N)

Génétique Médicale, CHR Clemenceau, CHU de Caen, Avenue Côte de Nacre, France.

H Mittre (H)

Génétique Médicale, CHR Clemenceau, CHU de Caen, Avenue Côte de Nacre, France.

M Laurans (M)

CRCM, CHU de Caen, Avenue Côte de Nacre, France.

D Guenet (D)

Laboratoire de Biochimie, Dépistage néonatal, CHU de Caen, Avenue Côte de Nacre, France.

J Brouard (J)

Pédiatrie, CHU de Caen, Avenue Côte de Nacre, France.

M Gerard (M)

Génétique Médicale, CHR Clemenceau, CHU de Caen, Avenue Côte de Nacre, France.

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Classifications MeSH