Effects of endocrine disruptor furan on reproductive physiology of Sprague Dawley rats: An F1 Extended One-Generation Reproductive Toxicity Study (EOGRTS).
Animals
Diet
Endocrine Disruptors
/ toxicity
Estrogens
/ blood
Female
Follicle Stimulating Hormone
/ blood
Furans
/ toxicity
Luteinizing Hormone
/ blood
Male
Ovary
/ drug effects
Pregnancy
Prenatal Exposure Delayed Effects
Progesterone
/ blood
Rats, Sprague-Dawley
Reproduction
/ drug effects
Testis
/ drug effects
Testosterone
/ blood
Toxicity Tests, Chronic
Extended One-Generation Reproductive Toxicity Study (EOGRTS)
Furan
histopathology
puberty
Journal
Human & experimental toxicology
ISSN: 1477-0903
Titre abrégé: Hum Exp Toxicol
Pays: England
ID NLM: 9004560
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
pubmed:
17
3
2020
medline:
20
2
2021
entrez:
17
3
2020
Statut:
ppublish
Résumé
The present study investigated the reproductive toxicity of furan in an Extended One-Generation Reproductive Toxicity Study in rats. Sprague Dawley F0 weaning rats (30 per sex per group) were exposed to furan orally at 0, 1, 2.5, 5, and 10 mg kg
Identifiants
pubmed: 32174189
doi: 10.1177/0960327120911416
doi:
Substances chimiques
Endocrine Disruptors
0
Estrogens
0
Furans
0
Testosterone
3XMK78S47O
Progesterone
4G7DS2Q64Y
Luteinizing Hormone
9002-67-9
Follicle Stimulating Hormone
9002-68-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM